Cytokeratin 5 Antikörper

Produktnummer ABIN965962

Produktdetails anti-Cytokeratin 5 Antikörper

Target: Cytokeratin 5 (KRT5) (Keratin 5 (KRT5))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Cytokeratin 5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Aufreinigung: Ascitic fluid

Immunogen: Purified recombinant fragment of Cytokeratin 5 expressed in E. Coli.

Klon: 1E1

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Western Bloting: 1/500 - 1/2000.
ELISA: Propose dilution 1/10000.
Not yet tested in other applications.
Determining optimal working dilutions by titration test.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Referenzen für anti-Cytokeratin 5 Antikörper (ABIN965962)

Gu, Kim, Ichiki, Park, Nagai, Kitajima: "A usual frameshift and delayed termination codon mutation in keratin 5 causes a novel type of epidermolysis bullosa simplex with migratory circinate erythema." in: The Journal of investigative dermatology, Vol. 121, Issue 3, pp. 482-5, (2003) (PubMed).

Details zu Cytokeratin 5

Target: Cytokeratin 5 (KRT5) (Keratin 5 (KRT5))

Andere Bezeichnung: Cytokeratin 5 (KRT5 Produkte)

Synonyme: 3300001P10Rik antikoerper, AW146334 antikoerper, CK5 antikoerper, K5 antikoerper, Krt2-5 antikoerper, Tfip8 antikoerper, DDD antikoerper, DDD1 antikoerper, EBS2 antikoerper, KRT5A antikoerper, Sak57 antikoerper, ckii antikoerper, wu:fb02h09 antikoerper, wu:fj02d02 antikoerper, wu:fk78b12 antikoerper, zfCKII antikoerper, KRT75 antikoerper, CK-5 antikoerper, Keratin-5 antikoerper, keratin 5 antikoerper, Krt5 antikoerper, KRT5 antikoerper, krt5 antikoerper

Hintergrund: Cytokeratin 5, also known as CK5, KRT5. It is a member of the keratin gene family. Biochemically, most members of the CK family fall into one of two classes, type I (acidic polypeptides) and type II (basic polypeptides). The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the basal layer of the epidermis with family member KRT14. The type II cytokeratins are clustered in a region of chromosome 12q12-q13. At least one member of the acidic family and one member of the basic family is expressed in all epithelial cells. Cytokeratin 5 is expressed in normal basal cells. Mutations of the Cytokeratin5 gene (KRT5) have been shown to result in the autosomal dominant disorderepidermolysis bullosa (EB). Defects in KRT5 are a cause of epidermolysis bullosa simplex.
Synonyms: K5, CK5, KRT5A, KRT5

Molekulargewicht: 62.3kDa

Gen-ID: 3852