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KRT8 Antikörper (AA 391-483)

Name: KRT8 Antikörper (AA 391-483)
Brand: antibodies-online
SKU: ABIN965965
Price: 594 EUR
Availability: InStock

KRT8 Reaktivität: Human WB, IF, IHC, ELISA Wirt: Maus Monoclonal 8A5D12 unconjugated

(2 Referenzen)

Produktnummer ABIN965965

Datenblatt (PDF)

Target Alle KRT8 Antikörper anzeigen

KRT8 (Keratin 8 (KRT8))
Bindungsspezifität
23

16

13

13

11

8

6

6

5

5

4

4

4

3

3

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 391-483
Reaktivität
266

86

82

33

33

31

30

16

14

10

8

5

4

3

2

1

1

1
Human
Wirt
148

126

3
Maus
Passende Sekundärantikörper
Klonalität
146

129
Monoklonal
Konjugat
145

22

16

9

4

4

4

4

4

4

3

3

3

3

3

3

3

3

3

3

3

3

3

3

3

3

3

3

2

2

2

1
Dieser KRT8 Antikörper ist unkonjugiert
Applikation
171

100

99

81

67

49

41

40

30

29

24

17

5

5

4

4

2

2

1

1
Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (IHC), ELISA

Aufreinigung

Ascitic fluid

Immunogen

Purified recombinant fragment of human Cytokeratin (aa391-483) expressed in E. Coli.

Klon

8A5D12

Isotyp

IgG1

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anti-Keratin 8 (KRT8) (AA 391-483) antibody
KRT8 Reaktivität: Human WB, IHC, ELISA, ICC Wirt: Maus Monoclonal 8A5D12 unconjugated

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KRT8 Reaktivität: Human, Ratte, Maus, Rind (Kuh), Hund, Meerschweinchen, Pferd, Saccharomyces cerevisiae WB, IHC Wirt: Kaninchen Polyclonal unconjugated

Applikationshinweise

Western Bloting: 1/500 - 1/2000.
Immunohistochemistry: 1/200 - 1/1000.
Immunofluorescence: 1/200 - 1/1000.
ELISA: Propose dilution 1/10000.
Not yet tested in other applications.
Determining optimal working dilutions by titration test.

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Konservierungsmittel

Sodium azide

Vorsichtsmaßnahmen

This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung

4 °C
Wang, He, Tsao, Cheung, Wong, Chiu: "Cytokeratin 8 silencing in human nasopharyngeal carcinoma cells leads to cisplatin sensitization." in: Cancer letters, Vol. 265, Issue 2, pp. 188-96, (2008) (PubMed).

Walker, Harris, Holloway, McKenzie, Wells, Robinson, Morris: "Cytokeratin KRT8/18 expression differentiates distinct subtypes of grade 3 invasive ductal carcinoma of the breast." in: Cancer genetics and cytogenetics, Vol. 178, Issue 2, pp. 94-103, (2007) (PubMed).
Target

KRT8 (Keratin 8 (KRT8))

Andere Bezeichnung

Cytokeratin 8 (KRT8 Produkte)

Synonyme

CARD2 antikoerper, CK-8 antikoerper, CK8 antikoerper, CYK8 antikoerper, K2C8 antikoerper, K8 antikoerper, KO antikoerper, AA960620 antikoerper, AL022697 antikoerper, AU019895 antikoerper, Card2 antikoerper, EndoA antikoerper, Krt-2.8 antikoerper, Krt2-8 antikoerper, CYKER antikoerper, KRT2-8 antikoerper, KERATIN8 antikoerper, ck8 antikoerper, cyk8 antikoerper, k2c8 antikoerper, card2 antikoerper, krt2-5 antikoerper, MGC69490 antikoerper, KRT8 antikoerper, DreK8 antikoerper, cb186 antikoerper, krt2-8 antikoerper, sb:cb186 antikoerper, wu:fa20h05 antikoerper, wu:fa95h10 antikoerper, wu:fb96c06 antikoerper, zf-K8 antikoerper, zfk8 antikoerper, DKFZp468F2127 antikoerper, keratin 8 antikoerper, keratin 8 S homeolog antikoerper, KRT8 antikoerper, Krt8 antikoerper, krt8.S antikoerper, krt8 antikoerper

Hintergrund

Cytokeratin 8, also known as CK8, KRT8, K8. Entrez Protein NP_002264. It is a member of the type II keratin family.Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells.It typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in this gene cause cryptogenic cirrhosis.
Synonyms: CK8, CYK8, K2C8, KRT8

Molekulargewicht

54kDa

Gen-ID

3856