Der1-Like Domain Family, Member 2 (DERL2) (N-Term) Antikörper

Produktnummer ABIN965991

Produktdetails

Target: Der1-Like Domain Family, Member 2 (DERL2)

Bindungsspezifität: N-Term

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Unkonjugiert

Applikation: Immunohistochemistry (IHC)

Aufreinigung: Purified by antigen-specific affinity chromatography.

Immunogen: Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to N-terminal residues of human DERL2 (Derlin-2)

Anwendungsinformationen

Applikationshinweise: ELISA, Western blotting: 1µg/ml for 2hrs.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: This antibody is stored in PBS, 50% glycerol

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Referenzen

Ying, Yu, Xu: "Cloning and characterization of F-LANa, upregulated in human liver cancer." in: Biochemical and biophysical research communications, Vol. 286, Issue 2, pp. 394-400, (2001) (PubMed).

Antigendetails

Target: Der1-Like Domain Family, Member 2 (DERL2)

Andere Bezeichnung: DERL2 (DERL2 Produkte)

Hintergrund: DERL2 (Derlin-2) may be involved in the degradation process of specific misfolded endoplasmic reticulum (ER) luminal proteins. Its precise role is however unclear. In contrast to DER1, it is not involved in the degradation of MHC class I heavy chains in cas of infection by the cytomegalovirus. DERL2 may play a role in cell proliferation.

Pathways: ER-Nucleus Signaling, Feeding Behaviour