Purified by antigen-specific affinity chromatography.
Immunogen
Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to N-terminal residues of human FOLR2 (Folate receptor beta precursor)
FOLR2
Reaktivität: Human
ELISA
Wirt: Kaninchen
Polyclonal
HRP
Applikationshinweise
ELISA, Western blotting: 1µg/ml for 2hrs.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Buffer
This antibody is stored in PBS, 50% glycerol
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
-20 °C
Sadasivan, Cedeno, Rothenberg: "Characterization of the gene encoding a folate-binding protein expressed in human placenta. Identification of promoter activity in a G-rich SP1 site linked with the tandemly repeated GGAAG motif for the ets encoded GA-binding protein." in: The Journal of biological chemistry, Vol. 269, Issue 7, pp. 4725-35, (1994) (PubMed).
Page, Owen, Price, Elwood: "Expression of the human placental folate receptor transcript is regulated in human tissues. Organization and full nucleotide sequence of the gene." in: Journal of molecular biology, Vol. 229, Issue 4, pp. 1175-83, (1993) (PubMed).
Ratnam, Marquardt, Duhring, Freisheim: "Homologous membrane folate binding proteins in human placenta: cloning and sequence of a cDNA." in: Biochemistry, Vol. 28, Issue 20, pp. 8249-54, (1990) (PubMed).
The FOLR2 (Folate receptor beta) binds to folate and reduced folic acid derivatives and mediates delivery of 5-methyltetrahydrofolate to the interior of cells.