GATA1
Reaktivität: Human
WB, ELISA
Wirt: Maus
Monoclonal
4G1
unconjugated
Applikationshinweise
Western Bloting: 1/500 - 1/2000. ELISA: Propose dilution 1/10000. Not yet tested in other applications. Determining optimal working dilutions by titration test.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
4 °C
Wierenga, Vellenga, Schuringa: "Down-regulation of GATA1 uncouples STAT5-induced erythroid differentiation from stem/progenitor cell proliferation." in: Blood, Vol. 115, Issue 22, pp. 4367-76, (2010) (PubMed).
Yerges, Klei, Cauley, Roeder, Kammerer, Moffett, Ensrud, Nestlerode, Marshall, Hoffman, Lewis, Lang, Barrett-Connor, Ferrell, Orwoll, Zmuda: "High-density association study of 383 candidate genes for volumetric BMD at the femoral neck and lumbar spine among older men." in: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, Vol. 24, Issue 12, pp. 2039-49, (2009) (PubMed).
Target
GATA1
(GATA Binding Protein 1 (Globin Transcription Factor 1) (GATA1))
Erythroid specific transcription factor,GATA sequence binding protein (same as EryF1,NF-E1,EF-1,EF gammaa,GF1),expressed in RBC,mast cell,megakaryocyte,hematopoietic progenitor cell,testis,associated with a special class of nuclear bodies,activated by erythropoietin,inactivated by coactivation of DEATH receptors (TNFRSF6) mediated caspase cleavage Tissue specificity: Erythrocytes Synonyms: GF1, GF-1, NFE1, XLTT, ERYF1, GATA-1, GATA1