EHMT1 Antikörper

Produktnummer ABIN966204

Produktdetails anti-EHMT1 Antikörper

Target: EHMT1 (Euchromatic Histone-Lysine N-Methyltransferase 1 (EHMT1))

Reaktivität: Human

Wirt: Bitte anfragen

Klonalität: Monoklonal

Konjugat: Dieser EHMT1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Spezifität: Ni-NTA purified truncated recombinant GLP expressed in E. Coli strain BL21 (DE3)

Aufreinigung: Antibodies are purified by protein A affinity chromatography

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Western Blot: Dilution 1: 200- 1: 1,000
ELISA: Propose dilution 1: 10,000
Determining optimal working dilutions by titration test.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Lagerung: -20 °C

Referenzen für anti-EHMT1 Antikörper (ABIN966204)

Young: "Inhibition of glucagon secretion." in: Advances in pharmacology (San Diego, Calif.), Vol. 52, pp. 151-71, (2006) (PubMed).

De León, Crutchlow, Ham, Stoffers: "Role of glucagon-like peptide-1 in the pathogenesis and treatment of diabetes mellitus." in: The international journal of biochemistry & cell biology, Vol. 38, Issue 5-6, pp. 845-59, (2006) (PubMed).

Details zu EHMT1

Target: EHMT1 (Euchromatic Histone-Lysine N-Methyltransferase 1 (EHMT1))

Andere Bezeichnung: GLP (EHMT1 Produkte)

Synonyme: EUHMTASE1 antikoerper, Eu-HMTase1 antikoerper, FP13812 antikoerper, GLP antikoerper, GLP1 antikoerper, KMT1D antikoerper, bA188C12.1 antikoerper, EHMT1 antikoerper, G9a antikoerper, 9230102N17Rik antikoerper, D330003E03 antikoerper, mKIAA1876 antikoerper, bZ1O1.6 antikoerper, si:rp71-1o1.6 antikoerper, zgc:136244 antikoerper, euchromatic histone lysine methyltransferase 1 antikoerper, histone-lysine N-methyltransferase EHMT2 antikoerper, euchromatic histone-lysine N-methyltransferase 1 antikoerper, euchromatic histone methyltransferase 1 antikoerper, euchromatic histone-lysine N-methyltransferase 1a antikoerper, EHMT1 antikoerper, Ehmt1 antikoerper, LOC100121084 antikoerper, ehmt1 antikoerper, ehmt1a antikoerper

Hintergrund: Glucagon-like peptide-1 (GLP-1) is an incretin hormone secreted from enteroendocrine L cells in response to ingested nutrients. The closely related peptides glucagon-like peptide (GLP-1) and glucagon have opposing effects on blood glucose. GLP-1 induces glucose-dependent insulin secretion in the pancreas, while glucagon stimulates gluconeogenesis and glycogenolysis in the liver. Glucagon is processed from a large precursor, proglucagon, in a tissue-specific manner in pancreatic alpha-cells. The identification of a hybrid peptide acting as both a GLP-1 agonist and a glucagon antagonist would provide a novel approach for the treatment of type 2 diabetes.

Gen-ID: 79813