HSD11B1 Antikörper (AA 131-145)
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- Target Alle HSD11B1 Antikörper anzeigen
- HSD11B1 (Hydroxysteroid (11-Beta) Dehydrogenase 1 (HSD11B1))
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Bindungsspezifität
- AA 131-145
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Reaktivität
- Human, Maus, Ratte
- Wirt
- Bitte anfragen
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Klonalität
- Polyklonal
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Konjugat
- Dieser HSD11B1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Immunogen
- A synthetic peptide corresponding to a sequence at the middle region of human HSD11B1 (131-145 aa), different from the mouse sequence by two amino acids.
- Top Product
- Discover our top product HSD11B1 Primärantikörper
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- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Rekonstitution
- 0.2ml of distilled water will yield a concentration of 500µg/ml.
- Buffer
- Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4
- Konservierungsmittel
- Thimerosal (Merthiolate), Sodium azide
- Lagerung
- -20 °C
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- Target
- HSD11B1 (Hydroxysteroid (11-Beta) Dehydrogenase 1 (HSD11B1))
- Andere Bezeichnung
- HSD11B1 (HSD11B1 Produkte)
- Synonyme
- 11-DH antikoerper, 11-beta-HSD1 antikoerper, CORTRD2 antikoerper, HDL antikoerper, HSD11 antikoerper, HSD11B antikoerper, HSD11L antikoerper, SDR26C1 antikoerper, hsd11 antikoerper, hsd11b antikoerper, LRRGT00065 antikoerper, hydroxysteroid 11-beta dehydrogenase 1 antikoerper, hydroxysteroid (11-beta) dehydrogenase 1b antikoerper, hydroxysteroid (11-beta) dehydrogenase 1 L homeolog antikoerper, HSD11B1 antikoerper, HSD11B1b antikoerper, hsd11b1.L antikoerper, Hsd11b1 antikoerper
- Hintergrund
- 11-hydroxysteroid dehydrogenase type 1 is an NADPH-dependent enzyme highly expressed in key metabolic tissues including liver, adipose tissue, and the central nervous system.In these tissues, HSD11B1 reduces cortisone to the active hormone cortisol that activates glucocorticoid receptors.It is inhibited by carbenoxolone, a drug typically used in the treatment of peptic ulcersTannin et al. (1991) localized the HSD11B1 gene to chromosome 1. The localization was confirmed by isolating the gene from a chromosome 1-specific library using the cDNA as a probe. Schutte et al. (2000) mapped the HSD11B1 gene to 1q32-q41.
- Pathways
- Metabolism of Steroid Hormones and Vitamin D, Steroid Hormone Biosynthesis, Regulation of Carbohydrate Metabolic Process
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