JAK2 Antikörper (AA 745-955)
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- Target Alle JAK2 Antikörper anzeigen
- JAK2 (Janus Kinase 2 (JAK2))
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Bindungsspezifität
- AA 745-955
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser JAK2 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA
- Aufreinigung
- Ascitic fluid
- Immunogen
- Purified recombinant fragment of JAK2(745-955aa) expressed in E. Coli.
- Klon
- 1C1
- Isotyp
- IgG1
- Top Product
- Discover our top product JAK2 Primärantikörper
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- Applikationshinweise
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Western Bloting: 1/500 - 1/2000.
ELISA: Propose dilution 1/10000.
Not yet tested in other applications.
Determining optimal working dilutions by titration test. - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C
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Contributions of leukemia inhibitory factor receptor and oncostatin M receptor to signal transduction in heterodimeric complexes with glycoprotein 130." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 163, Issue 12, pp. 6651-8, (2000) (PubMed).
: "The human homologue of the yeast proteins Skb1 and Hsl7p interacts with Jak kinases and contains protein methyltransferase activity." in: The Journal of biological chemistry, Vol. 274, Issue 44, pp. 31531-42, (1999) (PubMed).
: "Plasma levels of lipid and cholesterol oxidation products and cytokines in diabetes mellitus and cigarette smoking: effects of vitamin E treatment." in: Atherosclerosis, Vol. 129, Issue 2, pp. 169-76, (1997) (PubMed).
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Contributions of leukemia inhibitory factor receptor and oncostatin M receptor to signal transduction in heterodimeric complexes with glycoprotein 130." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 163, Issue 12, pp. 6651-8, (2000) (PubMed).
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- Target
- JAK2 (Janus Kinase 2 (JAK2))
- Andere Bezeichnung
- JAK2 (JAK2 Produkte)
- Synonyme
- JAK2bCA antikoerper, jak2 antikoerper, JTK10 antikoerper, THCYT3 antikoerper, AI504024 antikoerper, C81284 antikoerper, Fd17 antikoerper, JAK-2 antikoerper, Janus kinase 2b antikoerper, Janus kinase 2 antikoerper, jak2b antikoerper, JAK2 antikoerper, Jak2 antikoerper
- Hintergrund
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This gene product is a protein tyrosine kinase involved in a specific subset of cytokine receptor signaling pathways. It has been found to be constituitively associated with the prolactin receptor and is required for responses to gamma interferon. Mice that do not express an active protein for this gene exhibit embryonic lethality associated with the absence of definitive erythropoiesis.
Synonyms: JTK10, JAK2 - Molekulargewicht
- 130.6kDa
- Gen-ID
- 3717
- Pathways
- JAK-STAT Signalweg, RTK Signalweg, Interferon-gamma Pathway, Positive Regulation of Peptide Hormone Secretion, Intracellular Steroid Hormone Receptor Signaling Pathway, Response to Growth Hormone Stimulus, Positive Regulation of Endopeptidase Activity, Protein targeting to Nucleus, CXCR4-mediated Signaling Events, Platelet-derived growth Factor Receptor Signaling, Unfolded Protein Response
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