RAB25 Antikörper

Produktnummer ABIN966930

Produktdetails anti-RAB25 Antikörper

Target: RAB25 (RAB25, Member RAS Oncogene Family (RAB25))

Reaktivität: Human

Wirt: Bitte anfragen

Klonalität: Monoklonal

Konjugat: Dieser RAB25 Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB), Immunohistochemistry (IHC)

Spezifität: Ni-NTA purified recombinant Rab25 expressed in E. Coli strain BL21 (DE3)

Aufreinigung: Antibodies are purified by protein A affinity chromatography

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: Western Blot: 1: 500- 1: 2,000
IHC(P): 1: 500- 1: 2,000
IHC(F): 1: 500- 1: 2,000
ELISA: Propose dilution 1: 10,000.
Determining optimal working dilutions by titration test.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS with 0.2%BSA

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Referenzen für anti-RAB25 Antikörper (ABIN966930)

Goldenring, Shen, Vaughan, Modlin: "Identification of a small GTP-binding protein, Rab25, expressed in the gastrointestinal mucosa, kidney, and lung." in: The Journal of biological chemistry, Vol. 268, Issue 25, pp. 18419-22, (1993) (PubMed).

Details zu RAB25

Target: RAB25 (RAB25, Member RAS Oncogene Family (RAB25))

Andere Bezeichnung: Rab25 (RAB25 Produkte)

Synonyme: MGC84182 antikoerper, RAB25 antikoerper, catx-8 antikoerper, MGC79587 antikoerper, rab25 antikoerper, si:dkeyp-84f11.7 antikoerper, zgc:101648 antikoerper, CATX-8 antikoerper, RAB11C antikoerper, AV012978 antikoerper, RAB25, member RAS oncogene family L homeolog antikoerper, RAB25, member RAS oncogene family antikoerper, RAB25, member RAS oncogene family a antikoerper, rab25.L antikoerper, RAB25 antikoerper, rab25 antikoerper, rab25a antikoerper, Rab25 antikoerper

Hintergrund: Members of the Ras-related superfamily of GTP binding proteins, which includes Ras, Rho, Rab and ARF subfamilies, exhibit 30-50% similarity with Ras p21. Rab proteins play an important role for either in endocytosis or in biosynthetic protein transport. The possibility that Rab proteins might also direct the exocytosis from secretory vesicles to the plasma membrane is supported by the observation that in yeast, the SEC4 protein, which is 40% similar to Rab proteins, is associated with secretory vesicles. Rab proteins located on the cytoplasmic face of organelles and vesicles, rab proteins are involved in intracellular membrane fusion reactions. Rab25 was cloned from a gastric parietal cell cDNA library and is expressed in epithelial tissues such as the gastrointestinal mucosae, kidney, and lung, which encoded a protein of 28 kDa

Gen-ID: 57111