Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to near N-terminal residues of Baker's Yeast (Saccharomyces cerevisiae) STN1 (Protein STN1)
OBFC1
Reaktivität: Human
WB, ELISA
Wirt: Kaninchen
Polyclonal
APC
Beschränkungen
Nur für Forschungszwecke einsetzbar
Lagerung
4 °C
Albuquerque, Smolka, Payne, Bafna, Eng, Zhou: "A multidimensional chromatography technology for in-depth phosphoproteome analysis." in: Molecular & cellular proteomics : MCP, Vol. 7, Issue 7, pp. 1389-96, (2008) (PubMed).
Grandin, Damon, Charbonneau: "Ten1 functions in telomere end protection and length regulation in association with Stn1 and Cdc13." in: The EMBO journal, Vol. 20, Issue 5, pp. 1173-83, (2001) (PubMed).
Chandra, Hughes, Nugent, Lundblad: "Cdc13 both positively and negatively regulates telomere replication." in: Genes & development, Vol. 15, Issue 4, pp. 404-14, (2001) (PubMed).
Grandin, Reed, Charbonneau: "Stn1, a new Saccharomyces cerevisiae protein, is implicated in telomere size regulation in association with Cdc13." in: Genes & development, Vol. 11, Issue 4, pp. 512-27, (1997) (PubMed).
Coster, Jonniaux, Goffeau: "Analysis of a 32.8 kb segment of yeast chromosome IV reveals 21 open reading frames, including TPS2, PPH3, RAD55, SED1, PDC2, AFR1, SSS1, SLU7 and a tRNA for arginine." in: Yeast (Chichester, England), Vol. 11, Issue 7, pp. 673-9, (1995) (PubMed).
STN1 (Protein STN1) has a role in telomere length regulation and telomere end protection. Acts as an inhibitor of telomerase loading through its interaction with CDC13. STN1 (Protein STN1)interacts with CDC13 and TEN1. STN1 may localize in Telomere and it is similar to YDR082W STN1 Telomere end-binding and capping protein, plays a key role with Pol12p in linking telomerase action with completion of lagging strand synthesis, and in a regulatory step required for telomere capping. Synonyms: D4456, YD8554.15