Transferrin Receptor Antikörper
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- Target Alle Transferrin Receptor (TFRC) Antikörper anzeigen
- Transferrin Receptor (TFRC) (Transferrin Receptor (p90, CD71) (TFRC))
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser Transferrin Receptor Antikörper ist unkonjugiert
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Applikation
- Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Spezifität
- This antibody reacts with the transferrin receptor, a 180-190 kD transmembrane glycoprotein which exists as a 95 kD homodimer with interchain disulfide bond. The specificity of these antibodies, as demonstrated by immunoprecipitation, are equivalent to OKT9, B3/25 and BerT9.
- Aufreinigung
- Purified.
- Immunogen
- Cell line KG1.
- Klon
- B349(DF1513)
- Isotyp
- IgG1 kappa
- Top Product
- Discover our top product TFRC Primärantikörper
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- Applikationshinweise
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Immunofluorescense 10-20 micrograms/ml.
Flow cytometry: 1 micrograms/10^6 cells.
Immunohistochemistry: (Acetone-fixed frozen) 5-15 micrograms/mL using avidin-biotin system. This antibody is an indicator of proliferation activity. It also has prognostic significance when typing tumors, such as leukemias and lymphomas.
Staining Procedure: This antibody can be used on frozen tissue sections only in IHC. - Kommentare
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Cellular Localization: Cell membrane.
Recommended Positive Control: Tonsil - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 0.4 mg/ml.
- Buffer
- 0.2 mg Immunoglobulin in cell culture supernatant, 50 mM Sodium Borate, 150 mM Sodium Chloride, pH 8.0
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C
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Anti-transferrin receptor antibody and antibody-drug conjugates cross the blood-brain barrier." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 88, Issue 11, pp. 4771-5, (1991) (PubMed).
: "Role of the human transferrin receptor cytoplasmic domain in endocytosis: localization of a specific signal sequence for internalization." in: The Journal of cell biology, Vol. 110, Issue 2, pp. 283-94, (1990) (PubMed).
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Anti-transferrin receptor antibody and antibody-drug conjugates cross the blood-brain barrier." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 88, Issue 11, pp. 4771-5, (1991) (PubMed).
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- Target
- Transferrin Receptor (TFRC) (Transferrin Receptor (p90, CD71) (TFRC))
- Andere Bezeichnung
- Transferrin Receptor,CD71 (TFRC Produkte)
- Synonyme
- Trfr antikoerper, LOC100219280 antikoerper, tfr antikoerper, cd71 antikoerper, tfr1 antikoerper, trfr antikoerper, CD71 antikoerper, T9 antikoerper, TFR antikoerper, TFR1 antikoerper, TR antikoerper, TRFR antikoerper, p90 antikoerper, 2610028K12Rik antikoerper, AI195355 antikoerper, AI426448 antikoerper, AU015758 antikoerper, E430033M20Rik antikoerper, Mtvr-1 antikoerper, Mtvr1 antikoerper, transferrin receptor antikoerper, TFRC antikoerper, Tfrc antikoerper, tfrc antikoerper
- Molekulargewicht
- ~9095 kDa
- Gen-ID
- 7037
- Pathways
- Transition Metal Ion Homeostasis
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