TRIM25 Antikörper (N-Term)

Produktnummer ABIN967204

Produktdetails anti-TRIM25 Antikörper

Target: TRIM25 (Tripartite Motif Containing 25 (TRIM25))

Bindungsspezifität: N-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TRIM25 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC)

Immunogen: Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to N-terminal residues of human TRIM25 (Tripartite motif-containing protein 25)

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Lagerung: 4 °C

Referenzen für anti-TRIM25 Antikörper (ABIN967204)

Inoue, Orimo, Hosoi, Kondo, Toyoshima, Kondo, Ikegami, Ouchi, Orimo, Muramatsu: "Genomic binding-site cloning reveals an estrogen-responsive gene that encodes a RING finger protein." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 90, Issue 23, pp. 11117-21, (1994) (PubMed).

Details zu TRIM25

Target: TRIM25 (Tripartite Motif Containing 25 (TRIM25))

Andere Bezeichnung: TRIM25 (TRIM25 Produkte)

Synonyme: zgc:55773 antikoerper, MGC130751 antikoerper, EFP antikoerper, RNF147 antikoerper, Z147 antikoerper, ZNF147 antikoerper, AA960166 antikoerper, AL022677 antikoerper, Zfp147 antikoerper, Efp antikoerper, Znf147 antikoerper, E3 ubiquitin/ISG15 ligase TRIM25 antikoerper, tripartite motif containing 25 antikoerper, E3 ubiquitin/ISG15 ligase TRIM25-like L homeolog antikoerper, microRNA 3614 antikoerper, tripartite motif-containing 25 antikoerper, LOC100146440 antikoerper, trim25 antikoerper, LOC100490741.L antikoerper, TRIM25 antikoerper, MIR3614 antikoerper, Trim25 antikoerper

Hintergrund: TRIM25 (Tripartite motif-containing protein 25) is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a Bbox type 2, and a coiled-coil region. The protein localizes to the cytoplasm. The presence of potential DNA-binding and dimerization-transactivation domains suggests that this protein may act as a transcription factor, similar to several other members of the TRIM family. Expression of TRIM25 is upregulated in response to estrogen, and it is thought to mediate estrogen actions in breast cancer as a primary TRIM25 contains 1 B30.2/SPRY domain and 1 RING-type zinc finger.
Synonyms: EFP (Estrogen-responsive finger protein), RNF147 (RING finger protein 147), ZNF147 (Zinc finger protein 147)