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ASPSCR1 Antikörper

ASPSCR1 Reaktivität: Maus WB, ELISA Monoclonal unconjugated
Produktnummer ABIN967214
  • Target Alle ASPSCR1 Antikörper anzeigen
    ASPSCR1 (Alveolar Soft Part Sarcoma Chromosome Region, Candidate 1 (ASPSCR1))
    Reaktivität
    • 53
    • 20
    • 15
    • 5
    • 4
    • 1
    • 1
    Maus
    Wirt
    Bitte anfragen
    Klonalität
    • 74
    • 6
    Monoklonal
    Konjugat
    • 32
    • 8
    • 8
    • 7
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser ASPSCR1 Antikörper ist unkonjugiert
    Applikation
    • 61
    • 41
    • 13
    • 13
    • 6
    • 5
    • 4
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA
    Spezifität
    Ni-NTA purified truncated recombinant TUG expressed in E. Coli strain BL21 (DE3)
    Aufreinigung
    Antibodies are purified by protein A affinity chromatography
    Isotyp
    IgG1
    Top Product
    Discover our top product ASPSCR1 Primärantikörper
  • Applikationshinweise
    Western Blot: 1: 500- 1: 2,000
    ELISA: Propose dilution 1: 10,000.
    Determining optimal working dilutions by titration test.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Buffer
    PBS with 0.2%BSA
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
  • Bogan, Hendon, McKee, Tsao, Lodish: "Functional cloning of TUG as a regulator of GLUT4 glucose transporter trafficking." in: Nature, Vol. 425, Issue 6959, pp. 727-33, (2003) (PubMed).

  • Target
    ASPSCR1 (Alveolar Soft Part Sarcoma Chromosome Region, Candidate 1 (ASPSCR1))
    Andere Bezeichnung
    TUG (ASPSCR1 Produkte)
    Synonyme
    tug antikoerper, aspl antikoerper, asps antikoerper, rcc17 antikoerper, ubxd9 antikoerper, aspcr1 antikoerper, ASPCR1 antikoerper, ASPL antikoerper, ASPS antikoerper, RCC17 antikoerper, TUG antikoerper, UBXD9 antikoerper, UBXN9 antikoerper, 1190006K01Rik antikoerper, ASPC antikoerper, ASPSCR1, UBX domain containing tether for SLC2A4 antikoerper, alveolar soft part sarcoma chromosome region, candidate 1 S homeolog antikoerper, alveolar soft part sarcoma chromosome region, candidate 1 antikoerper, alveolar soft part sarcoma chromosome region, candidate 1 (human) antikoerper, ASPSCR1 antikoerper, aspscr1.S antikoerper, Aspscr1 antikoerper, aspscr1 antikoerper, Bm1_55980 antikoerper
    Hintergrund
    The TUG protein contains a UBX domain, for GLUT4. In truncated form, TUG acts in a dominantnegative manner to inhibit insulin-stimulated GLUT4 redistribution in Chinese hamster ovary cells and 3T3-L1 adipocytes. Full-length TUG forms a complex specifically with GLUT4. In 3T3-L1 adipocytes, this complex is present in unstimulated cells and is largely disassembled by insulin. Endogenous TUG is localized with the insulin-mobilizable pool of GLUT4 in unstimulated 3T3-L1 adipocytes, and is not mobilized to the plasma membrane by insulin.
    Gen-ID
    68938
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