VEGFR2 (Ab-951) antibody detects endogenous levels of total VEGFR2 protein.
Aufreinigung
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Immunogen
The antiserum was produced against synthesized non-phosphopeptide derived from human VEGFR2 around the phosphorylation site of tyrosine 951 (K-D-YP-V-G).
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
-20 °C
Zeng, Sanyal, Mukhopadhyay et al.: "Tyrosine residues 951 and 1059 of vascular endothelial growth factor receptor-2 (KDR) are essential for vascular permeability factor/vascular endothelial growth factor-induced endothelium migration ..." in: The Journal of biological chemistry, Vol. 276, Issue 35, pp. 32714-9, (2001) (PubMed).
Dougher, Terman: "Autophosphorylation of KDR in the kinase domain is required for maximal VEGF-stimulated kinase activity and receptor internalization." in: Oncogene, Vol. 18, Issue 8, pp. 1619-27, (1999) (PubMed).