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Cadherin 4 Antikörper (AA 22-201)

CDH4 Reaktivität: Maus, Ratte WB, IHC, IP Wirt: Maus Monoclonal 48-R unconjugated
Produktnummer ABIN967954
  • Target Alle Cadherin 4 (CDH4) Antikörper anzeigen
    Cadherin 4 (CDH4)
    Bindungsspezifität
    • 15
    • 10
    • 9
    • 5
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 22-201
    Reaktivität
    • 64
    • 22
    • 9
    • 5
    • 5
    • 2
    • 2
    • 1
    • 1
    Maus, Ratte
    Wirt
    • 59
    • 5
    • 1
    Maus
    Klonalität
    • 61
    • 4
    Monoklonal
    Konjugat
    • 26
    • 6
    • 5
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser Cadherin 4 Antikörper ist unkonjugiert
    Applikation
    • 53
    • 25
    • 21
    • 20
    • 14
    • 13
    • 13
    • 10
    • 9
    • 3
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP)
    Kreuzreaktivität
    Ratte (Rattus)
    Produktmerkmale
    1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
    2. Please refer to us for technical protocols.
    3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
    4. Source of all serum proteins is from USDA inspected abattoirs located in the United States.
    Aufreinigung
    The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
    Immunogen
    Mouse R-Cadherin aa. 22-201
    Klon
    48-R
    Isotyp
    IgG2a kappa
    Top Product
    Discover our top product CDH4 Primärantikörper
  • Kommentare

    Related Products: ABIN968545, ABIN967389

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    250 μg/mL
    Buffer
    Aqueous buffered solution containing BSA, glycerol, and ≤0.09 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store undiluted at -20°C.
  • Tanihara, Sano, Heimark, St John, Suzuki: "Cloning of five human cadherins clarifies characteristic features of cadherin extracellular domain and provides further evidence for two structurally different types of cadherin." in: Cell adhesion and communication, Vol. 2, Issue 1, pp. 15-26, (1995) (PubMed).

    Hutton, Christofori, Chi, Edman, Guest, Hanahan, Kelly: "Molecular cloning of mouse pancreatic islet R-cadherin: differential expression in endocrine and exocrine tissue." in: Molecular endocrinology (Baltimore, Md.), Vol. 7, Issue 9, pp. 1151-60, (1994) (PubMed).

    Matsunami, Miyatani, Inoue, Copeland, Gilbert, Jenkins, Takeichi: "Cell binding specificity of mouse R-cadherin and chromosomal mapping of the gene." in: Journal of cell science, Vol. 106 ( Pt 1), Issue 6, pp. 401-9, (1994) (PubMed).

  • Target
    Cadherin 4 (CDH4)
    Andere Bezeichnung
    R-Cadherin (CDH4 Produkte)
    Synonyme
    cad4 antikoerper, rcad antikoerper, R-cadherin antikoerper, cadherin-4 antikoerper, AW120700 antikoerper, R-Cadh antikoerper, Rcad antikoerper, Cdh4l antikoerper, zgc:136316 antikoerper, CAD4 antikoerper, RCAD antikoerper, cadherin 4 antikoerper, cadherin 4, type 1, R-cadherin (retinal) antikoerper, Cadherin-4 antikoerper, cdh4 antikoerper, Cdh4 antikoerper, CDH4 antikoerper, cdh-4 antikoerper
    Hintergrund
    R-Cadherin was first isolated from chicken retina, but was subsequently shown to be present and highly conserved in a variety of tissues from several different species. A 913 amino acid polypeptide, R-Cadherin is highly homologous to Cadherin-4, but is most closely related to another family member, N-Cadherin. In experiments using chimeric L cells expressing chicken or mouse Cadherins, those cells expressing mouse or chicken R-Cadherin were able to aggregate with each other as well as with cells expressing N-Cadherin. However, there was no aggregation of R-Cadherin expressing cells, with P- or E-Cadherin expressing cells. This suggests that the roles of specific cadherins are conserved among types in the determination of heterogenous cell segregation and distribution during tissue morphogenesis and maintenance.
    Molekulargewicht
    100 kDa
    Pathways
    Cell-Cell Junction Organization, Regulation of Cell Size
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