HSPA4 Antikörper (AA 703-858)

Produktnummer ABIN968011

Produktdetails anti-HSPA4 Antikörper

Target: HSPA4 (Heat Shock 70kDa Protein 4 (HSPA4))

Bindungsspezifität: AA 703-858

Reaktivität: Human, Maus, Ratte, Hund

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser HSPA4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)

Kreuzreaktivität: Ratte (Rattus), Human, Maus, Hund

Produktmerkmale: 1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2. Please refer to us for technical protocols.
3. Source of all serum proteins is from USDA inspected abattoirs located in the United States.
4. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.

Aufreinigung: The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

Immunogen: Hamster Hsp110 aa. 703-858

Klon: 21-Hsp110

Isotyp: IgG1

Anwendungsinformationen

Kommentare:

Related Products: ABIN968545, ABIN967389

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 250 μg/mL

Buffer: Aqueous buffered solution containing BSA, glycerol, and ≤0.09 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store undiluted at -20° C.

Referenzen für anti-HSPA4 Antikörper (ABIN968011)

Moore, Scheinman, Bellgrau: "The identification of a novel T cell activation state controlled by a diabetogenic gene." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 166, Issue 1, pp. 241-8, (2001) (PubMed).

Lee-Yoon, Easton, Murawski, Burd, Subjeck: "Identification of a major subfamily of large hsp70-like proteins through the cloning of the mammalian 110-kDa heat shock protein." in: The Journal of biological chemistry, Vol. 270, Issue 26, pp. 15725-33, (1995) (PubMed).

Details zu HSPA4

Target: HSPA4 (Heat Shock 70kDa Protein 4 (HSPA4))

Andere Bezeichnung: Hsp110 (HSPA4 Produkte)

Hintergrund: With the exception of Hsp110, the stress or heat shock proteins have been thoroughly characterized. Hsp110 has been reported to be expressed in most tissues. Like other stress proteins, Hsp110 is induced by heat shock and its induction is associated with thermotolerance. The sequence of Hsp110 reportedly bears similarity to several Hsp70-related proteins that have been termed Hsp110/SSE. The carboxy-terminal domains of these proteins and Hsp110 contain a putative peptide-binding site. These proteins also contain six highly conserved regions found in the same progression, as well as five conserved ATP-binding motifs. This antibody is routinely tested by western blot analysis.
Synonyms: Heat Shock Protein-110

Molekulargewicht: 110 kDa