ANKS1B Antikörper (AA 107-268)
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- Target Alle ANKS1B Antikörper anzeigen
- ANKS1B (Ankyrin Repeat and Sterile alpha Motif Domain Containing 1B (ANKS1B))
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Bindungsspezifität
- AA 107-268
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Reaktivität
- Human, Maus, Ratte, Huhn
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser ANKS1B Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
- Kreuzreaktivität
- Huhn, Maus, Ratte (Rattus)
- Produktmerkmale
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1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2. Please refer to us for technical protocols.
3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
4. Source of all serum proteins is from USDA inspected abattoirs located in the United States. - Aufreinigung
- The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
- Immunogen
- Human EB1 aa. 107-268
- Klon
- 5-EB1
- Isotyp
- IgG1
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- Kommentare
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Related Products: ABIN968536, ABIN967389
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 250 μg/mL
- Buffer
- Aqueous buffered solution containing BSA, glycerol, and ≤0.09 % sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store undiluted at -20°C.
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Cdc42 regulates GSK-3beta and adenomatous polyposis coli to control cell polarity." in: Nature, Vol. 421, Issue 6924, pp. 753-6, (2003) (PubMed).
: "Evidence that an interaction between EB1 and p150(Glued) is required for the formation and maintenance of a radial microtubule array anchored at the centrosome." in: Molecular biology of the cell, Vol. 13, Issue 10, pp. 3627-45, (2002) (PubMed).
: "Cytoplasmic linker proteins promote microtubule rescue in vivo." in: The Journal of cell biology, Vol. 159, Issue 4, pp. 589-99, (2002) (PubMed).
: "Repression of IRF-4 target genes in human T cell leukemia virus-1 infection." in: Oncogene, Vol. 21, Issue 44, pp. 6751-65, (2002) (PubMed).
: "Alternatively spliced variants of prostate-specific membrane antigen RNA: ratio of expression as a potential measurement of progression." in: Cancer research, Vol. 55, Issue 7, pp. 1441-3, (1995) (PubMed).
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Cdc42 regulates GSK-3beta and adenomatous polyposis coli to control cell polarity." in: Nature, Vol. 421, Issue 6924, pp. 753-6, (2003) (PubMed).
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- Target
- ANKS1B (Ankyrin Repeat and Sterile alpha Motif Domain Containing 1B (ANKS1B))
- Andere Bezeichnung
- EB1 (ANKS1B Produkte)
- Synonyme
- AIDA antikoerper, AIDA-1 antikoerper, ANKS2 antikoerper, EB-1 antikoerper, EB1 antikoerper, cajalin-2 antikoerper, AIDA-1b antikoerper, C030032C09Rik antikoerper, E530015N03Rik antikoerper, ENSMUSG00000078431 antikoerper, Gm10937 antikoerper, Gm1555 antikoerper, RGD1565556 antikoerper, si:ch211-146a9.3 antikoerper, si:dkey-11k24.3 antikoerper, Anks1b antikoerper, ankyrin repeat and sterile alpha motif domain containing 1B antikoerper, ankyrin repeat and sterile alpha motif domain-containing protein 1B antikoerper, ANKS1B antikoerper, Anks1b antikoerper, anks1b antikoerper, LOC100717398 antikoerper
- Hintergrund
- Familial adenomatous polyposis is an autosomal inherited disease characterized by mutations in the APC (adenomatous polyposis coli) gene. Individuals with this disease are predisposed to colorectal polyps and cancer. It has been proposed that disruption of the APC gene plays a role in the disease. APC is a large coiled-coil protein that interacts, via its carboxy terminus, with catenins and with the protein, EB1. This 30 kDa protein was discovered as a result of its strong binding to the C-terminal domain of APC. Like the APC-binding proteins beta-Catenin and pp120Cas, EB1 may play an essential role in modulating APC activity and tumorigenesis. This antibody is routinely tested by western blot analysis.
- Molekulargewicht
- 30 kDa
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