TFCP2 Antikörper (AA 205-414)

Produktnummer ABIN968193

Produktdetails anti-TFCP2 Antikörper

Target: TFCP2 (Transcription Factor CP2 (TFCP2))

Bindungsspezifität: AA 205-414

Reaktivität: Human, Maus, Ratte, Hund

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser TFCP2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF)

Kreuzreaktivität: Maus, Ratte (Rattus), Hund

Produktmerkmale: 1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2. Please refer to us for technical protocols.
3. Source of all serum proteins is from USDA inspected abattoirs located in the United States.
4. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.

Aufreinigung: The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

Immunogen: Human LSF aa. 205-414

Klon: 14-LSF

Isotyp: IgG1

Anwendungsinformationen

Kommentare:

Related Products: ABIN968551, ABIN967389

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 250 μg/mL

Buffer: Aqueous buffered solution containing BSA, glycerol, and ≤0.09 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store undiluted at -20° C.

Referenzen für anti-TFCP2 Antikörper (ABIN968193)

Volker, Rameh, Zhu, DeCaprio, Hansen: "Mitogenic stimulation of resting T cells causes rapid phosphorylation of the transcription factor LSF and increased DNA-binding activity." in: Genes & development, Vol. 11, Issue 11, pp. 1435-46, (1997) (PubMed).

Shirra, Zhu, Huang, Pallas, Hansen: "One exon of the human LSF gene includes conserved regions involved in novel DNA-binding and dimerization motifs." in: Molecular and cellular biology, Vol. 14, Issue 8, pp. 5076-87, (1994) (PubMed).

Details zu TFCP2

Target: TFCP2 (Transcription Factor CP2 (TFCP2))

Andere Bezeichnung: LSF (TFCP2 Produkte)

Synonyme: cp2 antikoerper, lsf antikoerper, sef antikoerper, lbp-1c antikoerper, tfcp2c antikoerper, MGC75945 antikoerper, TFCP2 antikoerper, lbp1c antikoerper, lsf1d antikoerper, TCFCP2 antikoerper, LBP1C antikoerper, LSF antikoerper, LSF1D antikoerper, SEF antikoerper, TFCP2C antikoerper, CP-2 antikoerper, CP2 antikoerper, D230015P20Rik antikoerper, LBP-1c antikoerper, LBP-1d antikoerper, LBP1 antikoerper, Tcfcp2 antikoerper, UBP-1 antikoerper, transcription factor CP2 antikoerper, transcription factor CP2 L homeolog antikoerper, tfcp2 antikoerper, TFCP2 antikoerper, tfcp2.L antikoerper, Tfcp2 antikoerper

Hintergrund: LSF (alphaCP2 or LBP-1c) is a transcription factor originally identified by its binding to, and induction of, the SV40 late promoter. LSF displays some similarity to the Elf-1/NTF transcription factors of Drosophila. It is primarily found in its dimeric form in solution, however it is the tetrameric form that recognizes a center-to-center 10 bp repeat. LSF-1D (LBP-1d) is the product of an alternative splicing event, resulting in a deletion of a 51 amino acid segment that corresponds with the DNA-binding region of LSF. LSF-1D is found in the cytoplasm, not in the nucleus, and can interact with LSF to form a heterotetramer that can interfere with LSF DNA binding. In mitogen-stimulated human peripheral T cells, LSF is phosphorylated on amino acid 291, which increases its DNA binding activity. Thus, LSF-mediated gene transcription is regulated by its phosphorylation and/or its interaction with LSF-1D during cell growth. This antibody is routinely tested by western blot analysis.
Synonyms: alphaCP2, LBP-1c

Molekulargewicht: 63 kDa