Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

Sorting Nexin 2 Antikörper (AA 15-137)

SNX2 Reaktivität: Human, Hund WB, IF Wirt: Maus Monoclonal 13-SNX2 unconjugated
Produktnummer ABIN968465
  • Target Alle Sorting Nexin 2 (SNX2) Antikörper anzeigen
    Sorting Nexin 2 (SNX2)
    Bindungsspezifität
    • 11
    • 9
    • 7
    • 5
    • 3
    • 2
    • 1
    • 1
    AA 15-137
    Reaktivität
    • 38
    • 8
    • 5
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human, Hund
    Wirt
    • 37
    • 1
    Maus
    Klonalität
    • 38
    Monoklonal
    Konjugat
    • 18
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser Sorting Nexin 2 Antikörper ist unkonjugiert
    Applikation
    • 29
    • 17
    • 6
    • 4
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF)
    Kreuzreaktivität
    Hund
    Produktmerkmale
    1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
    2. Please refer to us for technical protocols.
    3. Source of all serum proteins is from USDA inspected abattoirs located in the United States.
    4. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
    Aufreinigung
    The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
    Immunogen
    Human SNX2 aa. 15-137
    Klon
    13-SNX2
    Isotyp
    IgG1
    Top Product
    Discover our top product SNX2 Primärantikörper
  • Kommentare

    Related Products: ABIN968536, ABIN967389

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    250 μg/mL
    Buffer
    Aqueous buffered solution containing BSA, glycerol, and ≤0.09 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store undiluted at -20° C.
  • Haft, de la Luz Sierra, Barr, Haft, Taylor: "Identification of a family of sorting nexin molecules and characterization of their association with receptors." in: Molecular and cellular biology, Vol. 18, Issue 12, pp. 7278-87, (1998) (PubMed).

    Kurten, Cadena, Gill: "Enhanced degradation of EGF receptors by a sorting nexin, SNX1." in: Science (New York, N.Y.), Vol. 272, Issue 5264, pp. 1008-10, (1996) (PubMed).

  • Target
    Sorting Nexin 2 (SNX2)
    Andere Bezeichnung
    SNX2 (SNX2 Produkte)
    Synonyme
    snx2 antikoerper, MGC64590 antikoerper, SNX2 antikoerper, LOC100219194 antikoerper, TRG-9 antikoerper, 0610030A03Rik antikoerper, zgc:123293 antikoerper, sorting nexin 2 S homeolog antikoerper, sorting nexin 2 antikoerper, snx2.S antikoerper, SNX2 antikoerper, BACOIKO006_25 antikoerper, snx2 antikoerper, Snx2 antikoerper
    Hintergrund
    Biological processes such as transmembrane signaling and receptor mediated endocytosis revolve around the function of cell surface receptors. A network of molecular machinery directs the intracellular trafficking of receptors during their biosynthesis and mediates signaling downstream of receptors. The sorting nexins (SNX1, SNX1A, SNX2, SNX3, and SNX4) are a family of intracellular proteins that are thought to direct the sorting of receptor proteins. The SNX proteins contain a conserved 100 amino acid region termed the phox homology (PX) domain and are part of a family of hydrophilic proteins which includes S. cerevisiae proteins that function in protein sorting. SNX1, SNX2, and SNX4 associate predominantly with membranes and bind transmembrane receptors such as those for EGF, PDGF, and insulin. SNX1 directs the EGF receptor to the lysosomes for degradation. SNX2 forms homomeric complexes and heteromeric complexes with SNX1, SNX1A, and SNX4. These complexes are thought to be necessary for efficient protein sorting. Thus, SNX2 and other sorting nexins are thought to play important roles in the specificity of protein trafficking to and from the plasma membrane. This antibody is routinely tested by western blot analysis.
    Synonyms: Sorting Nexin-2
    Molekulargewicht
    72 kDa
Sie sind hier:
Kundenservice