GOLGA5 Antikörper (AA 510-713)

Produktnummer ABIN968506

Produktdetails anti-GOLGA5 Antikörper

Target: GOLGA5 (Golgin A5 (GOLGA5))

Bindungsspezifität: AA 510-713

Reaktivität: Human, Hund

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser GOLGA5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF)

Kreuzreaktivität: Hund

Produktmerkmale: 1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2. Please refer to us for technical protocols.
3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
4. Source of all serum proteins is from USDA inspected abattoirs located in the United States.

Aufreinigung: The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

Immunogen: Human Golgin-84 aa. 510-713

Klon: 26-Golgin

Isotyp: IgG1

Anwendungsinformationen

Kommentare:

Related Products: ABIN968552, ABIN967389

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 250 μg/mL

Buffer: Aqueous buffered solution containing BSA, glycerol, and ≤0.09 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store undiluted at -20° C.

Referenzen für anti-GOLGA5 Antikörper (ABIN968506)

Bascom, Srinivasan, Nussbaum: "Identification and characterization of golgin-84, a novel Golgi integral membrane protein with a cytoplasmic coiled-coil domain." in: The Journal of biological chemistry, Vol. 274, Issue 5, pp. 2953-62, (1999) (PubMed).

Details zu GOLGA5

Target: GOLGA5 (Golgin A5 (GOLGA5))

Andere Bezeichnung: Golgin-84 (GOLGA5 Produkte)

Synonyme: GOLIM5 antikoerper, RFG5 antikoerper, ret-II antikoerper, golim5 antikoerper, ret-ii antikoerper, rfg5 antikoerper, Ret-II antikoerper, im:7153094 antikoerper, sb:cb898 antikoerper, wu:fd50h11 antikoerper, zgc:66400 antikoerper, golgin A5 antikoerper, golgin A5 L homeolog antikoerper, golgi autoantigen, golgin subfamily a, 5 antikoerper, GOLGA5 antikoerper, golga5.L antikoerper, golga5 antikoerper, Golga5 antikoerper

Hintergrund: The Golgi apparatus is a complex and dynamic organelle that functions in protein sorting and modification. Numerous structural and regulatory proteins are involved in the budding, docking, and fusion of Golgi-directed vesicles. Golgin-84 is an integral membrane protein associated with the Golgi. Sequence analysis of the C-terminal region of Golgin-84 demonstrates a 14 residue region extending into the lumen of the Golgi, a membrane insertion sequence, and a Golgi retention signal. The large N-terminal cytoplasmic region contains a coiled-coil domain that is required for dimerization and two leucine zipper domains. Golgin-84 is ubiquitously expressed, but is abundant in testis. Golgin-84 has sequence homology to coiled-coil containing myosin family members and to several other Golgi proteins, including trans-Golgi p230 and gigantin. Trans-Golgi p230 has been implicated in the biogenesis of specific Golgi vesicles, while gigantin is implicated in the tethering of non-clathrin coated vesicles and in the anchoring of adjacent Golgi cisternae. Thus, Golgin-84 may have similar roles in vesicle biogenesis, docking, and fusion at the Golgi interface.

Molekulargewicht: 84 kDa