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MAP1B Antikörper (AA 1745-1858)

MAP1B Reaktivität: Human, Maus, Ratte WB Wirt: Maus Monoclonal 6-MAP1B unconjugated
Produktnummer ABIN968911
  • Target Alle MAP1B Antikörper anzeigen
    MAP1B (Microtubule-Associated Protein 1B (MAP1B))
    Bindungsspezifität
    • 16
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1745-1858
    Reaktivität
    • 33
    • 21
    • 21
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 33
    • 1
    Maus
    Klonalität
    • 33
    • 1
    Monoklonal
    Konjugat
    • 13
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser MAP1B Antikörper ist unkonjugiert
    Applikation
    • 14
    • 13
    • 13
    • 6
    • 6
    • 5
    • 5
    • 4
    • 3
    • 3
    • 3
    Western Blotting (WB)
    Kreuzreaktivität
    Human, Ratte (Rattus)
    Produktmerkmale
    1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
    2. Please refer to us for technical protocols.
    3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
    4. Source of all serum proteins is from USDA inspected abattoirs located in the United States.
    Aufreinigung
    The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
    Immunogen
    Mouse MAP1B aa. 1745-1858
    Klon
    6-MAP1B
    Isotyp
    IgG2a
    Top Product
    Discover our top product MAP1B Primärantikörper
  • Kommentare

    Related Products: ABIN967389

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    250 μg/mL
    Buffer
    Aqueous buffered solution containing BSA, glycerol, and ≤0.09 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store undiluted at -20° C.
  • Ma, Himes, Shea, Fischer: "Axonal transport of microtubule-associated protein 1B (MAP1B) in the sciatic nerve of adult rat: distinct transport rates of different isoforms." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 20, Issue 6, pp. 2112-20, (2000) (PubMed).

    Tögel, Wiche, Propst: "Novel features of the light chain of microtubule-associated protein MAP1B: microtubule stabilization, self interaction, actin filament binding, and regulation by the heavy chain." in: The Journal of cell biology, Vol. 143, Issue 3, pp. 695-707, (1998) (PubMed).

  • Target
    MAP1B (Microtubule-Associated Protein 1B (MAP1B))
    Andere Bezeichnung
    MAP1B (MAP1B Produkte)
    Synonyme
    FUTSCH antikoerper, MAP5 antikoerper, Mtap1b antikoerper, A230055D22 antikoerper, AI843217 antikoerper, LC1 antikoerper, Mtap-5 antikoerper, Mtap5 antikoerper, microtubule associated protein 1B antikoerper, microtubule-associated protein 1B antikoerper, MAP1B antikoerper, Map1b antikoerper
    Hintergrund
    Microtubule-associated proteins (MAPs) play a crucial role in the development and structure of nerve cells. These proteins are important for the assembly and stability of microtubles during neurite outgrowth and for the morphology of neuronal processes, such as dendrites. MAP1B encodes for a single precursor protein that is cleaved to produce a single heavy chain of 280 kDa and a light chain of 32 kDa which become noncovalently associated. Expression levels of MAP1B are reportedly highest in the brain and are modulated during development as reported with gene silencing experiments that implicate MAP1B's role during neuronal differentiation. In addition, MAP1B can be selectively phosphorylated depending on the cell type, subcellular localization and developmental phase. In neurons, MAP1B is expressed as a glycoprotein at the plasma membrane, where it can interact with proteins participating in axonal guiding. MAP1B has been reported to be observable to migrate in a range between 320-340 kDa. This antibody is routinely tested by western blot analysis.
    Molekulargewicht
    320-340 kDa
    Pathways
    Microtubule Dynamics, Regulation of Cell Size
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