Smooth Muscle Actin Antikörper

Produktnummer ABIN968947

Produktdetails anti-Smooth Muscle Actin Antikörper

Target: Smooth Muscle Actin (ACTA2) (Actin, alpha 2, Smooth Muscle, Aorta (ACTA2))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Smooth Muscle Actin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS), ELISA, Immunocytochemistry (ICC)

Verwendungszweck: ACTA2 Antibody

Aufreinigung: Ascitic fluid

Immunogen: Synthesized peptide of human ACTA2.

Klon: 4A4

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise:

ELISA: 1/10000

FCM: 1/200 - 1/400

ICC: 1/200 - 1/1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Referenzen für anti-Smooth Muscle Actin Antikörper (ABIN968947)

Shimojima, Yamamoto: "ACTA2 is not a major disease-causing gene for moyamoya disease." in: Journal of human genetics, Vol. 54, Issue 11, pp. 687-8, (2009) (PubMed).

Morisaki, Akutsu, Ogino, Kondo, Yamanaka, Tsutsumi, Yoshimuta, Okajima, Matsuda, Minatoya, Sasaki, Tanaka, Ishibashi-Ueda, Morisaki: "Mutation of ACTA2 gene as an important cause of familial and nonfamilial nonsyndromatic thoracic aortic aneurysm and/or dissection (TAAD)." in: Human mutation, Vol. 30, Issue 10, pp. 1406-11, (2009) (PubMed).

Details zu Smooth Muscle Actin

Target: Smooth Muscle Actin (ACTA2) (Actin, alpha 2, Smooth Muscle, Aorta (ACTA2))

Andere Bezeichnung: ACTA2 (ACTA2 Produkte)

Synonyme: AAT6 antikoerper, ACTSA antikoerper, MYMY5 antikoerper, GAMMA-ACTIN antikoerper, ACT antikoerper, ACTA3 antikoerper, ACTE antikoerper, ACTL3 antikoerper, ACTSG antikoerper, Act-4 antikoerper, Act4 antikoerper, SMGA antikoerper, 0610041G09Rik antikoerper, Actvs antikoerper, SMalphaA antikoerper, a-SMA antikoerper, alphaSMA antikoerper, wu:fb63d03 antikoerper, ASMA antikoerper, SMactin antikoerper, a-sma antikoerper, aat6 antikoerper, actsa antikoerper, mymy5 antikoerper, sm-actin antikoerper, ACTA2 antikoerper, actc1 antikoerper, ACT-4 antikoerper, asma antikoerper, ACTGE antikoerper, actin, alpha 2, smooth muscle, aorta antikoerper, actin, gamma 2, smooth muscle, enteric antikoerper, actin, alpha 2, smooth muscle, aorta L homeolog antikoerper, ACTA2 antikoerper, ACTG2 antikoerper, Actg2 antikoerper, Acta2 antikoerper, acta2 antikoerper, acta2.L antikoerper

Hintergrund:

Description: The protein encoded by this gene belongs to the actin family of proteins, which are highly conserved proteins that play a role in cell motility, structure and integrity. Alpha, beta and gamma actin isoforms have been identified, with alpha actins being a major constituent of the contractile apparatus, while beta and gamma actins are involved in the regulation of cell motility. This actin is an alpha actin that is found in skeletal muscle. Defects in this gene cause aortic aneurysm familial thoracic type 6. Multiple alternatively spliced variants, encoding the same protein, have been identified.

Aliases: AAT6, ACTSA, α-Smooth Muscle Actin

Molekulargewicht: 42kDa

Gen-ID: 59

HGNC: 59

UniProt: P62736

Pathways: Myometrial Relaxation and Contraction, Skeletal Muscle Fiber Development