APOA4
Reaktivität: Maus, Ratte
IHC, IF
Wirt: Kaninchen
Polyclonal
unconjugated
Applikationshinweise
ELISA: 1/10000
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Buffer
Ascitic fluid containing 0.03 % sodium azide.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
4 °C,-20 °C
Informationen zur Lagerung
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Chien, Chen, Hsu, Su, Chang, Lee, Lee: "Genetic association study of APOA1/C3/A4/A5 gene cluster and haplotypes on triglyceride and HDL cholesterol in a community-based population." in: Clinica chimica acta; international journal of clinical chemistry, Vol. 388, Issue 1-2, pp. 78-83, (2007) (PubMed).
Peignon, Thenet, Schreider, Fouquet, Ribeiro, Dussaulx, Chambaz, Cardot, Pinçon-Raymond, Le Beyec: "E-cadherin-dependent transcriptional control of apolipoprotein A-IV gene expression in intestinal epithelial cells: a role for the hepatic nuclear factor 4." in: The Journal of biological chemistry, Vol. 281, Issue 6, pp. 3560-8, (2006) (PubMed).
APOA4: apolipoprotein A-IV. Apoliprotein (apo) A-IV gene contains 3 exons separated by two introns. A sequence polymorphism has been identified in the 3'UTR of the third exon. The primary translation product is a 396-residue preprotein which after proteolytic processing is secreted its primary site of synthesis, the intestine, in association with chylomicron particles. Although its precise function is not known, apo A-IV is a potent activator of lecithin-cholesterol acyltransferase in vitro.