ARNTL Antikörper

Produktnummer ABIN968967

Produktdetails anti-ARNTL Antikörper

Target: ARNTL (Aryl Hydrocarbon Receptor Nuclear Translocator-Like (ARNTL))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser ARNTL Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC)

Verwendungszweck: ARNTL Antibody

Aufreinigung: Ascitic fluid

Immunogen: Purified recombinant fragment of human ARNTL expressed in E. Coli.

Klon: 1C5

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: ELISA: 1/10000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Referenzen für anti-ARNTL Antikörper (ABIN968967)

Yosifova, Mushiroda, Stoianov, Vazharova, Dimova, Karachanak, Zaharieva, Milanova, Madjirova, Gerdjikov, Tolev, Velkova, Kirov, Owen, ODonovan, Toncheva, Nakamura: "Case-control association study of 65 candidate genes revealed a possible association of a SNP of HTR5A to be a factor susceptible to bipolar disease in Bulgarian population." in: Journal of affective disorders, Vol. 117, Issue 1-2, pp. 87-97, (2009) (PubMed).

Lee, Lee, Lee, Park, Kang, Chung, Lee, Kim: "Dual modification of BMAL1 by SUMO2/3 and ubiquitin promotes circadian activation of the CLOCK/BMAL1 complex." in: Molecular and cellular biology, Vol. 28, Issue 19, pp. 6056-65, (2008) (PubMed).

Motzkus, Loumi, Cadenas, Vinson, Forssmann, Maronde: "Activation of human period-1 by PKA or CLOCK/BMAL1 is conferred by separate signal transduction pathways." in: Chronobiology international, Vol. 24, Issue 5, pp. 783-92, (2007) (PubMed).

Details zu ARNTL

Target: ARNTL (Aryl Hydrocarbon Receptor Nuclear Translocator-Like (ARNTL))

Andere Bezeichnung: ARNTL (ARNTL Produkte)

Synonyme: BMAL1 antikoerper, BMAL1c antikoerper, JAP3 antikoerper, MOP3 antikoerper, PASD3 antikoerper, TIC antikoerper, bHLHe5 antikoerper, Bmal1 antikoerper, ARNTL antikoerper, xBmal1 antikoerper, arntl antikoerper, Arnt3 antikoerper, BMAL1b antikoerper, bmal1b' antikoerper, aryl hydrocarbon receptor nuclear translocator like antikoerper, aryl hydrocarbon receptor nuclear translocator-like antikoerper, aryl hydrocarbon receptor nuclear translocator like S homeolog antikoerper, ARNTL antikoerper, Arntl antikoerper, arntl.S antikoerper, arntl antikoerper

Hintergrund:

Description: The protein encoded by this gene is a basic helix-loop-helix protein that forms a heterodimer with CLOCK. This complex binds an E-box upstream of the PER1 gene, activating this gene and possibly other circadian rhythym-associated genes. Three transcript variants encoding two different isoforms have been found for this gene.

Aliases: TIC, JAP3, MOP3, BMAL1, PASD3, BMAL1c, bHLHe5, MGC47515, ARNTL

Molekulargewicht: 68.7kDa

Gen-ID: 406

HGNC: 406

UniProt: O00327

Pathways: Regulation of Lipid Metabolism by PPARalpha, Protein targeting to Nucleus, Warburg Effekt