ATF2 Antikörper

Produktnummer ABIN968968

Produktdetails anti-ATF2 Antikörper

Target: ATF2 (Activating Transcription Factor 2 (ATF2))

Reaktivität: Human, Maus

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser ATF2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Aufreinigung: purified

Immunogen: Purified recombinant fragment of human ATF2 expressed in E. coli.

Klon: 4F12

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: 4°C, -20°C for long term storage

Referenzen für anti-ATF2 Antikörper (ABIN968968)

Chen, Takeuchi, Moroi, Hayashida, Kido, Chen, Tomoeda, Uenotsuchi, Tu, Furue, Urabe: "Overexpression of phosphorylated-ATF2 and STAT3 in cutaneous squamous cell carcinoma, Bowen's disease and basal cell carcinoma." in: Journal of dermatological science, Vol. 51, Issue 3, pp. 210-5, (2008) (PubMed).

Bhoumik, Singha, OConnell, Ronai: "Regulation of TIP60 by ATF2 modulates ATM activation." in: The Journal of biological chemistry, Vol. 283, Issue 25, pp. 17605-14, (2008) (PubMed).

Details zu ATF2

Target: ATF2 (Activating Transcription Factor 2 (ATF2))

Andere Bezeichnung: ATF2 (ATF2 Produkte)

Synonyme: CRE-BP1 antikoerper, CREB2 antikoerper, HB16 antikoerper, TREB7 antikoerper, CG12850 antikoerper, CG3749 antikoerper, dATF-2 antikoerper, DmelCG30420 antikoerper, CG30420 antikoerper, CHN1 antikoerper, Atf-2 antikoerper, CRE-BP antikoerper, Creb2 antikoerper, D130078H02Rik antikoerper, D18875 antikoerper, Tg(Gzma-Klra1)7Wum antikoerper, mXBP antikoerper, atf2-A antikoerper, atf2l antikoerper, activating transcription factor 2 antikoerper, Activating transcription factor-2 antikoerper, activating transcription factor 2 S homeolog antikoerper, ATF2 antikoerper, Atf-2 antikoerper, Atf2 antikoerper, atf2.S antikoerper, atf2 antikoerper

Hintergrund:

Description: This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds to the cAMP-responsive element (CRE), an octameric palindrome. The protein forms a homodimer or heterodimer with c-Jun and stimulates CRE-dependent transcription. The protein is also a histone acetyltransferase (HAT) that specifically acetylates histones H2B and H4 in vitro, thus it may represent a class of sequence-specific factors that activate transcription by direct effects on chromatin components. Additional transcript variants have been identified but their biological validity has not been determined.Tissue specificity: Abundant expression seen in the brain.

Aliases: HB16, CREB2, TREB7, CRE-BP1, MGC111558, ATF2

Molekulargewicht: 55 kDa

Gen-ID: 1386

HGNC: 1386

Pathways: MAPK Signalweg, RTK Signalweg, Thyroid Hormone Synthesis, Activation of Innate immune Response, Chromatin Binding, Myometrial Relaxation and Contraction, Synaptic Membrane, Tube Formation, Toll-Like Receptors Cascades