ATM Antikörper
(1 reference)-
- Target Alle ATM Antikörper anzeigen
- ATM (Ataxia Telangiectasia Mutated (ATM))
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser ATM Antikörper ist unkonjugiert
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Applikation
- ELISA
- Verwendungszweck
- ATM Antibody
- Aufreinigung
- Ascitic fluid
- Immunogen
- Purified recombinant fragment of human ATM expressed in E. Coli.
- Klon
- 5C5
- Isotyp
- IgG1
- Top Product
- Discover our top product ATM Primärantikörper
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anti-Ataxia Telangiectasia Mutated (ATM) (AA 1974-1988), (pSer1981) antibody
ATM Reaktivität: Human WB, IHC, ELISA, IP, IF, FACS, FM Wirt: Maus Monoclonal 10H11-E12 unconjugated
anti-Ataxia Telangiectasia Mutated (ATM) (AA 1974-1988), (pSer1981) antibodyATM Reaktivität: Human WB, IHC, ELISA, IP, IF, FACS, FM Wirt: Maus Monoclonal 10H11-E12 unconjugated
anti-Ataxia Telangiectasia Mutated (ATM) (C-Term) antibodyATM Reaktivität: Human, Maus WB, IHC, ELISA, IP, IF, FACS, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Ataxia Telangiectasia Mutated (ATM) (AA 2484-2748) antibodyATM Reaktivität: Human WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Ataxia Telangiectasia Mutated (ATM) (AA 2681-2750) antibodyATM Reaktivität: Human, Maus WB, ELISA, IHC (p), IF (p), IF (cc), FACS, IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-Ataxia Telangiectasia Mutated (ATM) antibodyATM Reaktivität: Human WB, IHC, ELISA, IP Wirt: Kaninchen Monoclonal 4E11 unconjugated Recombinant Antibody
anti-Ataxia Telangiectasia Mutated (ATM) (AA 1974-1988), (pSer1981) antibody (HRP)ATM Reaktivität: Human WB, IHC, ELISA, FM Wirt: Maus Monoclonal 10H11-E12 HRP
anti-Ataxia Telangiectasia Mutated (ATM) (AA 486-742) antibodyATM Reaktivität: Maus WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Ataxia Telangiectasia Mutated (ATM) antibodyATM Reaktivität: Human IHC, ELISA, FACS Wirt: Kaninchen Monoclonal 3G11 unconjugated Recombinant Antibody
anti-Ataxia Telangiectasia Mutated (ATM) (pSer1981) antibodyATM Reaktivität: Human IF, DB Wirt: Kaninchen Polyclonal RB8121 unconjugated
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- Applikationshinweise
- ELISA: 1/10000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- Ascitic fluid containing 0.03 % sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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: "ATM gene mutations result in both recessive and dominant expression phenotypes of genes and microRNAs." in: American journal of human genetics, Vol. 83, Issue 2, pp. 243-53, (2008) (PubMed).
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: "ATM gene mutations result in both recessive and dominant expression phenotypes of genes and microRNAs." in: American journal of human genetics, Vol. 83, Issue 2, pp. 243-53, (2008) (PubMed).
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- Target
- ATM (Ataxia Telangiectasia Mutated (ATM))
- Andere Bezeichnung
- ATM (ATM Produkte)
- Hintergrund
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Description: The protein encoded by this gene belongs to the PI3/PI4-kinase family. This protein is an important cell cycle checkpoint kinase that phosphorylates, thus, it functions as a regulator of a wide variety of downstream proteins, including tumor suppressor proteins p53 and BRCA1, checkpoint kinase CHK2, checkpoint proteins RAD17 and RAD9, and DNA repair protein NBS1. This protein and the closely related kinase ATR are thought to be master controllers of cell cycle checkpoint signaling pathways that are required for cell response to DNA damage and for genome stability. Mutations in this gene are associated with ataxia telangiectasia, an autosomal recessive disorder.Tissue specificity: Found in pancreas, kidney, skeletal muscle, liver, lung, placenta, brain, heart, spleen, thymus, testis, ovary, small intestine, colon and leukocytes.
Aliases: AT1, ATA, ATC, ATD, ATE, ATDC, TEL1, TELO1, MGC74674, DKFZp781A0353, ATM
- Molekulargewicht
- 351kDa
- Gen-ID
- 472
- HGNC
- 472
- UniProt
- Q13315
- Pathways
- p53 Signalweg, Apoptose, DNA Reparatur, Inositol Metabolic Process, Positive Regulation of Response to DNA Damage Stimulus
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