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Aurora A Antikörper

AURKA Reaktivität: Human WB, ELISA, ICC, FACS Wirt: Maus Monoclonal 1F8 unconjugated
Produktnummer ABIN968971
  • Target Alle Aurora A (AURKA) Antikörper anzeigen
    Aurora A (AURKA) (Aurora Kinase A (AURKA))
    Reaktivität
    • 112
    • 67
    • 38
    • 21
    • 18
    • 12
    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    Human
    Wirt
    • 107
    • 17
    • 1
    Maus
    Klonalität
    • 100
    • 24
    Monoklonal
    Konjugat
    • 76
    • 8
    • 5
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser Aurora A Antikörper ist unkonjugiert
    Applikation
    • 90
    • 47
    • 32
    • 25
    • 15
    • 11
    • 9
    • 7
    • 6
    • 3
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Flow Cytometry (FACS)
    Verwendungszweck
    AURKA Antibody
    Aufreinigung
    Ascitic fluid
    Immunogen
    Purified recombinant fragment of human AURKA expressed in E. Coli.
    Klon
    1F8
    Isotyp
    IgG1
    Top Product
    Discover our top product AURKA Primärantikörper
  • Applikationshinweise

    ELISA: 1/10000

    FCM: 1/200 - 1/400

    ICC: 1/200 - 1/1000

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Ascitic fluid containing 0.03 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Veerakumarasivam, Goldstein, Saeb-Parsy, Scott, Warren, Thorne, Mills, Venkitaraman, Neal, Kelly: "AURKA overexpression accompanies dysregulation of DNA-damage response genes in invasive urothelial cell carcinoma." in: Cell cycle (Georgetown, Tex.), Vol. 7, Issue 22, pp. 3525-33, (2008) (PubMed).

    De Luca, Brunetto, Asteriti, Giubettini, Lavia, Guarguaglini: "Aurora-A and ch-TOG act in a common pathway in control of spindle pole integrity." in: Oncogene, Vol. 27, Issue 51, pp. 6539-49, (2008) (PubMed).

  • Target
    Aurora A (AURKA) (Aurora Kinase A (AURKA))
    Andere Bezeichnung
    AURKA (AURKA Produkte)
    Hintergrund

    Description: Aurora A plays a role in cell cycle regulation during anaphase and/or telophase, in relation to the function of the centrosome/spindle pole region during chromosome segregation. Aurora A plays a key role during tumor development and progression and is overexpressed in many human cancers including breast, ovarian and colorectal. Aurora A is viewed as a potential target for anticancer drug treatment.Tissue specificity: Highly expressed in testis and weakly in skeletal muscle, thymus and spleen. Also highly expressed in colon, ovarian, prostate, neuroblastoma, breast and cervical cancer cell lines.

    Aliases: AIK, ARK1, AURA, BTAK, STK6, STK7, STK15, AURORA2, MGC34538, AURKA

    Molekulargewicht
    48kDa
    Gen-ID
    6790
    HGNC
    6790
    UniProt
    O14965
    Pathways
    Zellzyklus, Asymmetric Protein Localization
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