Aurora A Antikörper
-
- Target Alle Aurora A (AURKA) Antikörper anzeigen
- Aurora A (AURKA) (Aurora Kinase A (AURKA))
-
Reaktivität
- Human
-
Wirt
- Maus
-
Klonalität
- Monoklonal
-
Konjugat
- Dieser Aurora A Antikörper ist unkonjugiert
-
Applikation
- Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Flow Cytometry (FACS)
- Verwendungszweck
- AURKA Antibody
- Aufreinigung
- Ascitic fluid
- Immunogen
- Purified recombinant fragment of human AURKA expressed in E. Coli.
- Klon
- 1F8
- Isotyp
- IgG1
- Top Product
- Discover our top product AURKA Primärantikörper
-
-
- Applikationshinweise
-
ELISA: 1/10000
FCM: 1/200 - 1/400
ICC: 1/200 - 1/1000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Liquid
- Buffer
- Ascitic fluid containing 0.03 % sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
-
-
AURKA overexpression accompanies dysregulation of DNA-damage response genes in invasive urothelial cell carcinoma." in: Cell cycle (Georgetown, Tex.), Vol. 7, Issue 22, pp. 3525-33, (2008) (PubMed).
: "Aurora-A and ch-TOG act in a common pathway in control of spindle pole integrity." in: Oncogene, Vol. 27, Issue 51, pp. 6539-49, (2008) (PubMed).
: "
-
AURKA overexpression accompanies dysregulation of DNA-damage response genes in invasive urothelial cell carcinoma." in: Cell cycle (Georgetown, Tex.), Vol. 7, Issue 22, pp. 3525-33, (2008) (PubMed).
-
- Target
- Aurora A (AURKA) (Aurora Kinase A (AURKA))
- Andere Bezeichnung
- AURKA (AURKA Produkte)
- Hintergrund
-
Description: Aurora A plays a role in cell cycle regulation during anaphase and/or telophase, in relation to the function of the centrosome/spindle pole region during chromosome segregation. Aurora A plays a key role during tumor development and progression and is overexpressed in many human cancers including breast, ovarian and colorectal. Aurora A is viewed as a potential target for anticancer drug treatment.Tissue specificity: Highly expressed in testis and weakly in skeletal muscle, thymus and spleen. Also highly expressed in colon, ovarian, prostate, neuroblastoma, breast and cervical cancer cell lines.
Aliases: AIK, ARK1, AURA, BTAK, STK6, STK7, STK15, AURORA2, MGC34538, AURKA
- Molekulargewicht
- 48kDa
- Gen-ID
- 6790
- HGNC
- 6790
- UniProt
- O14965
- Pathways
- Zellzyklus, Asymmetric Protein Localization
-