BID Antikörper
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- Target Alle BID Antikörper anzeigen
- BID (BH3 Interacting Domain Death Agonist (BID))
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser BID Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunocytochemistry (ICC)
- Aufreinigung
- purified
- Immunogen
- Purified recombinant fragment of human BID expressed in E. coli.
- Klon
- 3C5
- Isotyp
- IgG1
- Top Product
- Discover our top product BID Primärantikörper
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- Applikationshinweise
- ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000, ICC: 1:200 - 1:1000, FCM: 1:200 - 1:400
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- Ascitic fluid containing 0.03 % sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
- 4°C, -20°C for long term storage
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- Target
- BID (BH3 Interacting Domain Death Agonist (BID))
- Andere Bezeichnung
- BID (BID Produkte)
- Synonyme
- FP497 antikoerper, 2700049M22Rik antikoerper, AI875481 antikoerper, AU022477 antikoerper, BID antikoerper, bid antikoerper, si:ch211-238n5.6 antikoerper, fp497 antikoerper, xbid antikoerper, DKFZp469E066 antikoerper, BH3 interacting domain death agonist antikoerper, BH3 interacting domain death agonist S homeolog antikoerper, BID antikoerper, Bid antikoerper, bida antikoerper, bid.S antikoerper, bid antikoerper
- Hintergrund
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Description: This gene encodes a death agonist that heterodimerizes with either agonist BAX or antagonist BCL2. The encoded protein is a member of the BCL-2 family of cell death regulators. It is a mediator of mitochondrial damage induced by caspase-8 (CASP8), CASP8 cleaves this encoded protein, and the COOH-terminal part translocates to mitochondria where it triggers cytochrome c release. Multiple alternatively spliced transcript variants have been found, but the full-length nature of some variants has not been defined.Tissue specificity: Isoform 2 and isoform 3 are expressed in spleen, bone marrow, cerebral and cerebellar cortex. Isoform 2 is expressed in spleen, pancreas and placenta (at protein level). Isoform 3 is expressed in lung, pancreas and spleen (at protein level). Isoform 4 is expressed in lung and pancreas (at protein level)
Aliases: FP497, MGC15319, MGC42355, BID
- Molekulargewicht
- 22 kDa
- Gen-ID
- 637
- HGNC
- 637
- Pathways
- Apoptose, Caspase Kaskade in der Apoptose, Positive Regulation of Endopeptidase Activity
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