BID Antikörper

Produktnummer ABIN968979

Produktdetails anti-BID Antikörper

Target: BID (BH3 Interacting Domain Death Agonist (BID))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser BID Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunocytochemistry (ICC)

Verwendungszweck: BID Antibody

Aufreinigung: Ascitic fluid

Immunogen: Purified recombinant full length protein of human BID expressed in E. Coli

Klon: 3C5

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise:

ELISA: 1/10000

FCM: 1/200 - 1/400

ICC: 1/200 - 1/1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Referenzen für anti-BID Antikörper (ABIN968979)

Wan, Liu, Xing, Chen: "Bid is required in NPe6-PDT-induced apoptosis." in: Photochemistry and photobiology, Vol. 84, Issue 1, pp. 250-7, (2008) (PubMed).

Wu, Xing, Chen, Wang: "Bid is not required for Bax translocation during UV-induced apoptosis." in: Cellular signalling, Vol. 19, Issue 12, pp. 2468-78, (2007) (PubMed).

Details zu BID

Target: BID (BH3 Interacting Domain Death Agonist (BID))

Andere Bezeichnung: BID (BID Produkte)

Synonyme: FP497 antikoerper, 2700049M22Rik antikoerper, AI875481 antikoerper, AU022477 antikoerper, BID antikoerper, bid antikoerper, si:ch211-238n5.6 antikoerper, fp497 antikoerper, xbid antikoerper, DKFZp469E066 antikoerper, BH3 interacting domain death agonist antikoerper, BH3 interacting domain death agonist S homeolog antikoerper, BID antikoerper, Bid antikoerper, bida antikoerper, bid.S antikoerper, bid antikoerper

Hintergrund:

Description: This gene encodes a death agonist that heterodimerizes with either agonist BAX or antagonist BCL2. The encoded protein is a member of the BCL-2 family of cell death regulators. It is a mediator of mitochondrial damage induced by caspase-8 (CASP8), CASP8 cleaves this encoded protein, and the COOH-terminal part translocates to mitochondria where it triggers cytochrome c release. Multiple alternatively spliced transcript variants have been found, but the full-length nature of some variants has not been defined.Tissue specificity: Isoform 2 and isoform 3 are expressed in spleen, bone marrow, cerebral and cerebellar cortex. Isoform 2 is expressed in spleen, pancreas and placenta (at protein level). Isoform 3 is expressed in lung, pancreas and spleen (at protein level). Isoform 4 is expressed in lung and pancreas (at protein level)

Aliases: FP497, MGC15319, MGC42355, BID

Molekulargewicht: 22kDa

Gen-ID: 637

HGNC: 637

UniProt: P55957

Pathways: Apoptose, Caspase Kaskade in der Apoptose, Positive Regulation of Endopeptidase Activity