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BLK Antikörper

BLK Reaktivität: Human WB, ELISA, IHC Wirt: Maus Monoclonal 9D10B7 unconjugated
Produktnummer ABIN968981
  • Target Alle BLK Antikörper anzeigen
    BLK (B Lymphoid Tyrosine Kinase (BLK))
    Reaktivität
    • 66
    • 24
    • 15
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 54
    • 9
    • 1
    Maus
    Klonalität
    • 56
    • 10
    Monoklonal
    Konjugat
    • 35
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser BLK Antikörper ist unkonjugiert
    Applikation
    • 50
    • 37
    • 28
    • 13
    • 13
    • 8
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    Verwendungszweck
    BLK Antibody
    Aufreinigung
    Ascitic fluid
    Immunogen
    Purified recombinant fragment of BLK expressed in E. Coli.
    Klon
    9D10B7
    Isotyp
    IgG1
    Top Product
    Discover our top product BLK Primärantikörper
  • Applikationshinweise
    ELISA: 1/10000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Ascitic fluid containing 0.03 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Tretter, Ross, Dordai, Desiderio: "Mimicry of pre-B cell receptor signaling by activation of the tyrosine kinase Blk." in: The Journal of experimental medicine, Vol. 198, Issue 12, pp. 1863-73, (2003) (PubMed).

  • Target
    BLK (B Lymphoid Tyrosine Kinase (BLK))
    Andere Bezeichnung
    BLK (BLK Produkte)
    Synonyme
    bltk antikoerper, si:dkey-33i22.2 antikoerper, zgc:136231 antikoerper, MODY11 antikoerper, BLK proto-oncogene, Src family tyrosine kinase antikoerper, B lymphoid kinase antikoerper, blk antikoerper, BLK antikoerper, Blk antikoerper
    Hintergrund

    Description: BLK ( B lymphoid tyrosine kinase), with 505-amino acid protein (about 56KDa), belongs to the Src non-receptor tyrosine kinases family.Different subcellular localizations of Src-family kinases may be important for the regulation of specific cellular processes such as mitogenesis, cytoskeletal organization, and membrane trafficking.Blk is expressed exclusively by B lymphocytes and it is thought to function in a signal transductory pathway specific to this lineage. B lymphoid expression of an active Blk mutant caused proliferation of B progenitor cells and enhanced responsiveness of these cells to interleukin 7. Thus, sustained activation of Blk induces responses normally associated with the pre-BCR.

    Aliases: MGC10442

    Gen-ID
    640
    HGNC
    640
    UniProt
    P51451
    Pathways
    Positive Regulation of Peptide Hormone Secretion, CXCR4-mediated Signaling Events, Thromboxane A2 Receptor Signaling
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