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BMI1 Antikörper

BMI1 Reaktivität: Human ELISA, IHC, ICC, FACS Wirt: Maus Monoclonal 3E3 unconjugated
Produktnummer ABIN968985
  • Target Alle BMI1 Antikörper anzeigen
    BMI1 (BMI1 Polycomb Ring Finger Oncogene (BMI1))
    Reaktivität
    • 112
    • 47
    • 27
    • 11
    • 8
    • 7
    • 7
    • 6
    • 5
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 78
    • 32
    • 6
    Maus
    Klonalität
    • 81
    • 35
    Monoklonal
    Konjugat
    • 76
    • 9
    • 9
    • 6
    • 5
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser BMI1 Antikörper ist unkonjugiert
    Applikation
    • 93
    • 50
    • 42
    • 21
    • 12
    • 12
    • 11
    • 6
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC), Flow Cytometry (FACS)
    Verwendungszweck
    BMI1 Antibody
    Aufreinigung
    Ascitic fluid
    Immunogen
    Purified recombinant fragment of human BMI1 expressed in E. Coli.
    Klon
    3E3
    Isotyp
    IgG1
    Top Product
    Discover our top product BMI1 Primärantikörper
  • Applikationshinweise

    ELISA: 1/10000

    FCM: 1/200 - 1/400

    ICC: 1/200 - 1/1000

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Ascitic fluid containing 0.03 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Edwards, Witherspoon, Wang, Afrasiabi, Pham, Birnbaumer, Lipkin: "Epigenetic repression of DNA mismatch repair by inflammation and hypoxia in inflammatory bowel disease-associated colorectal cancer." in: Cancer research, Vol. 69, Issue 16, pp. 6423-9, (2009) (PubMed).

    Bhattacharya, Nicoloso, Arvizo, Wang, Cortez, Rossi, Calin, Mukherjee: "MiR-15a and MiR-16 control Bmi-1 expression in ovarian cancer." in: Cancer research, Vol. 69, Issue 23, pp. 9090-5, (2009) (PubMed).

  • Target
    BMI1 (BMI1 Polycomb Ring Finger Oncogene (BMI1))
    Andere Bezeichnung
    BMI1 (BMI1 Produkte)
    Synonyme
    FLVI2/BMI1 antikoerper, PCGF4 antikoerper, RNF51 antikoerper, AW546694 antikoerper, Bmi-1 antikoerper, Pcgf4 antikoerper, bmi1 antikoerper, pcgf4 antikoerper, psc1 antikoerper, wu:fb17g03 antikoerper, wu:fd18f06 antikoerper, BMI-1 antikoerper, pcgf4b antikoerper, bmi-1 antikoerper, bmi1-a antikoerper, bmi1-b antikoerper, bmi1b antikoerper, rnf51 antikoerper, xbmi-1 antikoerper, BMI1 proto-oncogene, polycomb ring finger antikoerper, BMI1 polycomb ring finger oncogene antikoerper, Bmi1 polycomb ring finger oncogene antikoerper, bmi1 polycomb ring finger oncogene 1a antikoerper, bmi1 polycomb ring finger oncogene 1b antikoerper, BMI1 proto-oncogene, polycomb ring finger L homeolog antikoerper, BMI1 antikoerper, LOC100230513 antikoerper, Bmi1 antikoerper, bmi1a antikoerper, bmi1b antikoerper, bmi1.L antikoerper
    Hintergrund

    Description: Component of the Polycomb group (PcG) multiprotein PRC1 complex, a complex required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones, it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. In the PRC1 complex, it is required to stimulate the E3 ubiquitin-protein ligase activity of RNF2/RING2.

    Aliases: PCGF4, RNF51, MGC12685, FLVI2/BMI1

    Molekulargewicht
    37kDa
    Gen-ID
    648
    HGNC
    648
    UniProt
    P35226
    Pathways
    Zellzyklus, Autophagie
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