BTK Antikörper
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- Target Alle BTK Antikörper anzeigen
- BTK (Bruton Agammaglobulinemia tyrosine Kinase (BTK))
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Reaktivität
- Human, Affe
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser BTK Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC)
- Verwendungszweck
- BTK Antibody
- Aufreinigung
- Ascitic fluid
- Immunogen
- Purified recombinant fragment of BTK expressed in E. Coli.
- Klon
- 7F12H4
- Isotyp
- IgG1
- Top Product
- Discover our top product BTK Primärantikörper
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anti-Bruton Agammaglobulinemia tyrosine Kinase (BTK) (AA 30-240) antibody
BTK Reaktivität: Human WB, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Bruton Agammaglobulinemia tyrosine Kinase (BTK) antibodyBTK Reaktivität: Human WB, IHC, IF Wirt: Kaninchen Monoclonal unconjugated
anti-Bruton Agammaglobulinemia tyrosine Kinase (BTK) (AA 27-55) antibodyBTK Reaktivität: Human WB, ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Bruton Agammaglobulinemia tyrosine Kinase (BTK) (AA 209-239) antibodyBTK Reaktivität: Human WB, ELISA, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Bruton Agammaglobulinemia tyrosine Kinase (BTK) (AA 254-443) antibodyBTK Reaktivität: Human WB, ELISA, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Bruton Agammaglobulinemia tyrosine Kinase (BTK) (pSer180) antibodyBTK Reaktivität: Maus, Ratte WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-Bruton Agammaglobulinemia tyrosine Kinase (BTK) (AA 209-239) antibodyBTK Reaktivität: Human WB, IF, IHC (p) Wirt: Kaninchen Polyclonal RB03117 unconjugated
anti-Bruton Agammaglobulinemia tyrosine Kinase (BTK) (AA 27-55), (N-Term) antibodyBTK Reaktivität: Human WB, IHC (p) Wirt: Kaninchen Polyclonal RB33691 unconjugated
anti-Bruton Agammaglobulinemia tyrosine Kinase (BTK) (C-Term) antibodyBTK Reaktivität: Human, Maus WB, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-Bruton Agammaglobulinemia tyrosine Kinase (BTK) (Internal Region) antibodyBTK Reaktivität: Human, Maus, Ratte WB, ELISA, IHC, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
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- Applikationshinweise
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ELISA: 1/10000
ICC: 1/200 - 1/1000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- Ascitic fluid containing 0.03 % sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- Target
- BTK (Bruton Agammaglobulinemia tyrosine Kinase (BTK))
- Andere Bezeichnung
- BTK (BTK Produkte)
- Hintergrund
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Description: Brutons tyrosine kinase (BTK) is a member of the BTK/Tec family of cytoplasmic tyrosine kinases.All members of the family contain SH3 and SH2 domains and, with the exception of Txk and Dsrc28C, also contain a pleckstrin homology (PH) and a Tec homology (TH) domain in their amino termini.BTK plays an important role in B cell development. Activation of B cells by various ligands is accompanied by BTK membrane translocation mediated by its PH domain binding to phosphatidylinositol-3,4,5-trisphosphate. The membrane located BTK is active and associated with transient phosphorylation of two tyrosine residues, Tyr551 and Tyr223. Tyr551 in the activation loop is transphosphorylated by the Src family tyrosine kinase, leading to autophosphorylation at Tyr223 within the SH3 domain, which is necessary for full activation.
Aliases: BTK
- Molekulargewicht
- 77kDa
- Gen-ID
- 695
- HGNC
- 695
- UniProt
- Q06187
- Pathways
- Fc-epsilon Rezeptor Signalübertragung, Hormone Transport, Activation of Innate immune Response, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Toll-Like Receptors Cascades, BCR Signaling
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