c-Rel Antikörper

Produktnummer ABIN968997

Produktdetails anti-c-Rel Antikörper

Target: c-Rel (REL proto-oncogene (c-Rel))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser c-Rel Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC)

Verwendungszweck: c-Rel Antibody

Aufreinigung: Ascitic fluid

Immunogen: Purified recombinant fragment of human c-Rel expressed in E. Coli.

Klon: 1E7

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise:

ELISA: 1/10000

ICC: 1/200 - 1/1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Referenzen für anti-c-Rel Antikörper (ABIN968997)

Trynka, Zhernakova, Romanos, Franke, Hunt, Turner, Bruinenberg, Heap, Platteel, Ryan, de Kovel, Holmes, Howdle, Walters, Sanders, Mulder, Mearin, Verbeek, Trimble, Stevens, Kelleher, Barisani et al.: "Coeliac disease-associated risk variants in TNFAIP3 and REL implicate altered NF-kappaB signalling. ..." in: Gut, Vol. 58, Issue 8, pp. 1078-83, (2009) (PubMed).

Garbati, Gilmore: "Ser484 and Ser494 in REL are the major sites of IKK phosphorylation in vitro: evidence that IKK does not directly enhance GAL4-REL transactivation." in: Gene expression, Vol. 14, Issue 4, pp. 195-205, (2008) (PubMed).

Details zu c-Rel

Target: c-Rel (REL proto-oncogene (c-Rel))

Andere Bezeichnung: c-Rel (c-Rel Produkte)

Synonyme: C-Rel antikoerper, c-Rel antikoerper, NFkB antikoerper, c-rel antikoerper, zgc:100833 antikoerper, Xrel2 antikoerper, Xrel3 antikoerper, rel antikoerper, rel-A antikoerper, rel2 antikoerper, rel3 antikoerper, v-rel antikoerper, xrel antikoerper, REL proto-oncogene, NF-kB subunit antikoerper, reticuloendotheliosis oncogene antikoerper, RELA proto-oncogene, NF-kB subunit antikoerper, v-rel avian reticuloendotheliosis viral oncogene homolog antikoerper, v-rel avian reticuloendotheliosis viral oncogene homolog L homeolog antikoerper, ribonuclease A family member 2 pseudogene antikoerper, REL antikoerper, Rel antikoerper, Rela antikoerper, rel antikoerper, rel.L antikoerper, ECRP antikoerper

Hintergrund:

Description: The REL gene encodes c-Rel, a transcription factor that is a member of the Rel/NFKB family, which also includes RELA (MIM 164014), RELB (604758), NFKB1 (MIM 164011), and NFKB2 (MIM 164012). These proteins are related through a highly conserved N-terminal region termed the 'Rel domain,' which is responsible for DNA binding, dimerization, nuclear localization, and binding to the NFKB inhibitor.

Aliases: Rel, c-Rel

Molekulargewicht: 68.5kDa

Gen-ID: 5966

HGNC: 5966

UniProt: Q04864