CD94 Antikörper

Produktnummer ABIN969031

Produktdetails anti-CD94 Antikörper

Target: CD94 (KLRD1) (Killer Cell Lectin-Like Receptor Subfamily D, Member 1 (KLRD1))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD94 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), ELISA

Verwendungszweck: CD94 Antibody

Aufreinigung: Ascitic fluid

Immunogen: Purified recombinant fragment of human CD94 expressed in E. Coli.

Klon: 1H1

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise:

ELISA: 1/10000

FCM: 1/200 - 1/400

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Referenzen für anti-CD94 Antikörper (ABIN969031)

Lonigro, Mirabile, Munda, Barchitta, Bottino, Fazzio, Di Cataldo, Agodi, Schilirò: "Association between high expression of natural killer related-genes (NCAM/CD94) and early death during induction in children with acute myeloid leukemia." in: Leukemia, Vol. 22, Issue 9, pp. 1778-81, (2008) (PubMed).

Masilamani, Narayanan, Prieto, Borrego, Coligan: "Uncommon endocytic and trafficking pathway of the natural killer cell CD94/NKG2A inhibitory receptor." in: Traffic (Copenhagen, Denmark), Vol. 9, Issue 6, pp. 1019-34, (2008) (PubMed).

Details zu CD94

Target: CD94 (KLRD1) (Killer Cell Lectin-Like Receptor Subfamily D, Member 1 (KLRD1))

Andere Bezeichnung: CD94 (KLRD1 Produkte)

Synonyme: CD94 antikoerper, CD94-B antikoerper, Cd94 antikoerper, killer cell lectin like receptor D1 antikoerper, killer cell lectin-like receptor subfamily D, member 1 antikoerper, killer cell lectin-like receptor, subfamily D, member 1 antikoerper, KLRD1 antikoerper, Klrd1 antikoerper

Hintergrund:

Description: Natural killer (NK) cells are a distinct lineage of lymphocytes that mediate cytotoxic activity and secrete cytokines upon immune stimulation. Several genes of the C-type lectin superfamily, including members of the NKG2 family, are expressed by NK cells and may be involved in the regulation of NK cell function. KLRD1 (CD94) is an antigen preferentially expressed on NK cells and is classified as a type II membrane protein because it has an external C terminus. Plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells. Tissue specificity: Natural killer cells.

Aliases: CD94, KLRD1

Molekulargewicht: 21kDa

Gen-ID: 3824

HGNC: 3824

UniProt: Q13241