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N-Cadherin Antikörper

Name: N-Cadherin Antikörper
Brand: antibodies-online
SKU: ABIN969038
Price: 562.94 EUR
Availability: InStock

CDH2 Reaktivität: Human WB, IHC, FACS, ELISA, ICC Wirt: Maus Monoclonal 5D5 unconjugated

Western blot analysis using CDH2 mouse mAb against A431 (1), NIH/3T3 (2), Hela (3), C6 (4) and LNCap (5) cell lysate. (N-Cadherin Antikörper)

Flow cytometric analysis of PC-2 cells using CDH2 mouse mAb (green) and negative control (purple). (N-Cadherin Antikörper)

FACS

Immunofluorescence analysis of A431 cells using CDH2 mouse mAb (green). (N-Cadherin Antikörper)

Immunohistochemical analysis of paraffin-embedded human Placenta tissues using CDH2 mouse mAb (N-Cadherin Antikörper)

IHC

Immunohistochemical analysis of paraffin-embedded human lung cancer (A), colon cancer (B), ovarian cancer (C) and mammary cancer(D), using CDH2 mouse mAb with DAB staining. (N-Cadherin Antikörper)

IHC

5 Abbildungen

(2 Referenzen)

Produktnummer ABIN969038

Datenblatt (PDF)

Target Alle N-Cadherin (CDH2) Antikörper anzeigen

N-Cadherin (CDH2) (Cadherin 2 (CDH2))
Reaktivität
146

93

68

21

16

15

8

4

3

3

3

3

2

2

2

2

2

1

1

1
Human
Wirt
92

61

4

4

2
Maus
Passende Sekundärantikörper
Klonalität
85

78
Monoklonal
Konjugat
83

15

5

4

4

4

3

3

3

3

3

3

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1
Dieser N-Cadherin Antikörper ist unkonjugiert
Applikation
114

54

43

41

25

24

17

14

13

12

12

8

4

2

2

1

1

1

1

1

1
Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS), ELISA, Immunocytochemistry (ICC)

Verwendungszweck

CDH2 Antibody

Aufreinigung

Ascitic fluid

Immunogen

Purified recombinant fragment of human CDH2 expressed in E. Coli.

Klon

5D5

Isotyp

IgG1

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anti-Cadherin 2 (CDH2) (AA 690-770) antibody
CDH2 Reaktivität: Human, Maus, Ratte WB, IF, ELISA, IHC (p) Wirt: Kaninchen Polyclonal unconjugated

anti-Cadherin 2 (CDH2) (AA 450-550) antibody
CDH2 Reaktivität: Human WB, IHC, IF Wirt: Kaninchen Polyclonal unconjugated

anti-Cadherin 2 (CDH2) (AA 685-784) antibody
CDH2 Reaktivität: Human WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated

anti-Cadherin 2 (CDH2) (AA 295-414) antibody
CDH2 Reaktivität: Ratte WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated

anti-Cadherin 2 (CDH2) antibody
CDH2 Reaktivität: Human WB, IHC, IHC (f) Wirt: Kaninchen Monoclonal unconjugated Recombinant Antibody

anti-Cadherin 2 (CDH2) (Extracellular Domain) antibody
CDH2 Reaktivität: Human WB, IHC, IF, FACS, IHC (f) Wirt: Maus Monoclonal 8C11 unconjugated

Applikationshinweise

ELISA: 1/10000
FCM: 1/200 - 1/400
ICC: 1/200 - 1/1000

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Buffer

Ascitic fluid containing 0.03 % sodium azide.

Konservierungsmittel

Sodium azide

Vorsichtsmaßnahmen

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung

4 °C,-20 °C

Informationen zur Lagerung

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Wallerand, Cai, Wainberg, Garraway, Lascombe, Nicolle, Thiery, Bittard, Radvanyi, Reiter: "Phospho-Akt pathway activation and inhibition depends on N-cadherin or phospho-EGFR expression in invasive human bladder cancer cell lines." in: Urologic oncology, Vol. 28, Issue 2, pp. 180-8, (2010) (PubMed).

Sharma, Henderson: "IQ-domain GTPase-activating protein 1 regulates beta-catenin at membrane ruffles and its role in macropinocytosis of N-cadherin and adenomatous polyposis coli." in: The Journal of biological chemistry, Vol. 282, Issue 11, pp. 8545-56, (2007) (PubMed).
Target

N-Cadherin (CDH2) (Cadherin 2 (CDH2))

Andere Bezeichnung

CDH2 (CDH2 Produkte)

Synonyme

CD325 antikoerper, CDHN antikoerper, CDw325 antikoerper, NCAD antikoerper, N-cadherin antikoerper, cadherin-2 antikoerper, cdhn antikoerper, ncad antikoerper, cdw325 antikoerper, CDH2 antikoerper, Cadherin-2 antikoerper, Ncad antikoerper, glo antikoerper, lyr antikoerper, pac antikoerper, wu:fb47h04 antikoerper, cadherin 2 antikoerper, cadherin 2 S homeolog antikoerper, cadherin 2, type 1, N-cadherin (neuronal) antikoerper, CDH2 antikoerper, cdh2.S antikoerper, cdh2 antikoerper, Cdh2 antikoerper

Hintergrund

Description: This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. The protein functions during gastrulation and is required for establishment of left-right asymmetry. At certain central nervous system synapses, presynaptic to postsynaptic adhesion is mediated at least in part by this gene product.
Aliases: CDHN, NCAD, CD325, CDw325, CDH2

Molekulargewicht

99.8kDa

Gen-ID

1000

HGNC

1000

UniProt

P19022

Pathways

Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Synaptic Membrane