Chitotriosidase 1 Antikörper (AA 22-137)

Produktnummer ABIN969053

Produktdetails anti-Chitotriosidase 1 Antikörper

Target: Chitotriosidase 1 (CHIT1) (Chitotriosidase (CHIT1))

Bindungsspezifität: AA 22-137

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Chitotriosidase 1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Aufreinigung: purified

Immunogen: Purified recombinant fragment of CHIT1 (aa22-137) expressed in E. coli.

Klon: 1D9G2

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: ELISA: 1:10000, WB: 1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: 4°C, -20°C for long term storage

Referenzen für anti-Chitotriosidase 1 Antikörper (ABIN969053)

Wajner, Michelin, Burin, Pires, Pereira, Giugliani, Coelho et al.: "Comparison between the biochemical properties of plasma chitotriosidase from normal individuals and from patients with Gaucher disease, GM1-gangliosidosis, Krabbe disease and heterozygotes for ..." in: Clinical biochemistry, Vol. 40, Issue 5-6, pp. 365-9, (2007) (PubMed).

Bargagli, Margollicci, Perrone, Luddi, Perari, Bianchi, Refini, Grosso, Volterrani, Rottoli: "Chitotriosidase analysis in bronchoalveolar lavage of patients with sarcoidosis." in: Sarcoidosis, vasculitis, and diffuse lung diseases : official journal of WASOG / World Association of Sarcoidosis and Other Granulomatous Disorders, Vol. 24, Issue 1, pp. 59-64, (2007) (PubMed).

Details zu Chitotriosidase 1

Target: Chitotriosidase 1 (CHIT1) (Chitotriosidase (CHIT1))

Andere Bezeichnung: CHIT1 (CHIT1 Produkte)

Synonyme: CHI3 antikoerper, CHIT antikoerper, CHITD antikoerper, CHIT1 antikoerper, chio antikoerper, 2300002L19Rik antikoerper, chitinase 1 antikoerper, chitinase 1 (chitotriosidase) antikoerper, CHIT1 antikoerper, chit1 antikoerper, Chit1 antikoerper

Hintergrund:

Description: CHIT1:chitinase 1 (chitotriosidase). Chitotriosidase is a 50 kDa secreted glycoprotein that belongs to glycohydrolase family # 18. It is secreted by activated human macrophages and is markedly elevated in plasma of Gaucher disease patients. The expression of chitotriosidase occurs only at a late stage of differentiation of monocytes to activated macrophages in culture. Human macrophages can synthesize a functional chitotriosidase, a highly conserved enzyme with a strongly regulated expression. This enzyme may play a role in the degradation of chitin-containing pathogens.

Aliases: Chitotriosidase,CHI3, CHIT, FLJ00314, MGC125322, CHIT1

Gen-ID: 1118

HGNC: 1118