IKK alpha Antikörper (AA 500-590)

Produktnummer ABIN969054

Produktdetails anti-IKK alpha Antikörper

Target: IKK alpha (CHUK) (conserved Helix-Loop-Helix Ubiquitous Kinase (CHUK))

Bindungsspezifität: AA 500-590

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser IKK alpha Antikörper ist unkonjugiert

Applikation: ELISA

Verwendungszweck: CHUK Antibody

Aufreinigung: Ascitic fluid

Immunogen: Purified recombinant fragment of CHUK (aa500-590) expressed in E. Coli.

Klon: 7C10B6

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: ELISA: 1/10000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Referenzen für anti-IKK alpha Antikörper (ABIN969054)

Prajapati, Verma, Yamamoto, Kwak, Gaynor: "Protein phosphatase 2Cbeta association with the IkappaB kinase complex is involved in regulating NF-kappaB activity." in: The Journal of biological chemistry, Vol. 279, Issue 3, pp. 1739-46, (2004) (PubMed).

Details zu IKK alpha

Target: IKK alpha (CHUK) (conserved Helix-Loop-Helix Ubiquitous Kinase (CHUK))

Andere Bezeichnung: CHUK (CHUK Produkte)

Synonyme: ikk antikoerper, ikk1 antikoerper, ikka antikoerper, ikkalpha antikoerper, CHUK antikoerper, IKBKA antikoerper, IKK-alpha antikoerper, IKK1 antikoerper, IKKA antikoerper, NFKBIKA antikoerper, TCF16 antikoerper, AI256658 antikoerper, Chuk1 antikoerper, Fbx24 antikoerper, Fbxo24 antikoerper, Ikka antikoerper, zgc:56539 antikoerper, conserved helix-loop-helix ubiquitous kinase S homeolog antikoerper, conserved helix-loop-helix ubiquitous kinase antikoerper, chuk.S antikoerper, CHUK antikoerper, Chuk antikoerper, chuk antikoerper

Hintergrund:

Description: CHUK: conserved helix-loop-helix ubiquitous kinase. This gene encodes a member of the serine/threonine protein kinase family. The encoded protein, a component of a cytokine-activated protein complex that is an inhibitor of the essential transcription factor NF-kappa-B complex, phosphorylates sites that trigger the degradation of the inhibitor via the ubiquination pathway, thereby activating the transcription factor.

Aliases: IKK1, IKKA, IKBKA

Gen-ID: 1147

HGNC: 1147

UniProt: O15111

Pathways: PI3K-Akt Signalweg, NF-kappaB Signalweg, RTK Signalweg, T-Zell Rezeptor Signalweg, TLR Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades, BCR Signaling, Ubiquitin Proteasome Pathway, S100 Proteine