CRTC3 Antikörper
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- Target Alle CRTC3 Antikörper anzeigen
- CRTC3 (CREB Regulated Transcription Coactivator 3 (CRTC3))
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser CRTC3 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunocytochemistry (ICC)
- Verwendungszweck
- CRTC3 Antibody
- Aufreinigung
- Ascitic fluid
- Immunogen
- Purified recombinant fragment of human CRTC3 expressed in E. Coli.
- Klon
- 5G9
- Isotyp
- IgG1
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- Applikationshinweise
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ELISA: 1/10000
ICC: 1/200 - 1/1000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- Ascitic fluid containing 0.03 % sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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Clinicopathological significance of the CRTC3-MAML2 fusion transcript in mucoepidermoid carcinoma." in: Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, Vol. 22, Issue 12, pp. 1575-81, (2009) (PubMed).
: "A new type of MAML2 fusion in mucoepidermoid carcinoma." in: Genes, chromosomes & cancer, Vol. 47, Issue 3, pp. 203-6, (2008) (PubMed).
: "
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Clinicopathological significance of the CRTC3-MAML2 fusion transcript in mucoepidermoid carcinoma." in: Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, Vol. 22, Issue 12, pp. 1575-81, (2009) (PubMed).
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- Target
- CRTC3 (CREB Regulated Transcription Coactivator 3 (CRTC3))
- Andere Bezeichnung
- CRTC3 (CRTC3 Produkte)
- Synonyme
- torc3 antikoerper, MGC146372 antikoerper, 2610312F20Rik antikoerper, 6332415K15Rik antikoerper, AI429792 antikoerper, BC011210 antikoerper, TORC3 antikoerper, RGD1309666 antikoerper, TORC-3 antikoerper, CREB regulated transcription coactivator 3 antikoerper, CREB regulated transcription coactivator 3 L homeolog antikoerper, CRTC3 antikoerper, crtc3 antikoerper, Crtc3 antikoerper, crtc3.L antikoerper
- Hintergrund
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Description: Transcriptional coactivator for CREB1 which activates transcription through both consensus and variant cAMP response element (CRE) sites. Acts as a coactivator, in the SIK/TORC signaling pathway, being active when dephosphorylated and acts independently of CREB1 'Ser-133' phosphorylation. Enhances the interaction of CREB1 with TAF4. Regulates the expression of specific CREB-activated genes such as the steroidogenic gene, StAR. Potent coactivator of PPARGC1A and inducer of mitochondrial biogenesis in muscle cells. Also coactivator for TAX activation of the human T-cell leukemia virus type 1 (HTLV-1) long terminal repeats (LTR) .Tissue specificity: Predominantly expressed in B and T lymphocytes. Highest levels in lung. Also expressed in brain, colon, heart, kidney, ovary, and prostate. Weak expression in liver, pancreas, muscle, small intestine, spleen and stomach.
Aliases: TORC3, FLJ21868, CRTC3
- Molekulargewicht
- 68kDa
- Gen-ID
- 64784
- HGNC
- 64784
- UniProt
- Q6UUV7
- Pathways
- SARS-CoV-2 Protein Interaktom, Phosphorylierungen bei SARS-CoV-2 Infektion
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