Cortactin Antikörper
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- Target Alle Cortactin (CTTN) Antikörper anzeigen
- Cortactin (CTTN)
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser Cortactin Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA
- Verwendungszweck
- CTTN Antibody
- Aufreinigung
- Ascitic fluid
- Immunogen
- Purified recombinant fragment of human CTTN expressed in E. Coli.
- Klon
- 4C6
- Isotyp
- IgG1
- Top Product
- Discover our top product CTTN Primärantikörper
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- Applikationshinweise
- ELISA: 1/10000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- Ascitic fluid containing 0.03 % sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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[Expression and clinical significance of EMS1 gene in gastric carcinoma]." in: Ai zheng = Aizheng = Chinese journal of cancer, Vol. 27, Issue 3, pp. 323-6, (2008) (PubMed).
: "Association of cortactin, fascin-1 and epidermal growth factor receptor (EGFR) expression in ovarian carcinomas: correlation with clinicopathological parameters." in: Disease markers, Vol. 25, Issue 1, pp. 17-26, (2008) (PubMed).
: "
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[Expression and clinical significance of EMS1 gene in gastric carcinoma]." in: Ai zheng = Aizheng = Chinese journal of cancer, Vol. 27, Issue 3, pp. 323-6, (2008) (PubMed).
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- Target
- Cortactin (CTTN)
- Andere Bezeichnung
- CTTN (CTTN Produkte)
- Hintergrund
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Description: This gene is overexpressed in breast cancer and squamous cell carcinomas of the head and neck. The encoded protein is localized in the cytoplasm and in areas of the cell-substratum contacts. This gene has two roles: (1) regulating the interactions between components of adherens-type junctions and (2) organizing the cytoskeleton and cell adhesion structures of epithelia and carcinoma cells. During apoptosis, the encoded protein is degraded in a caspase-dependent manner. The aberrant regulation of this gene contributes to tumor cell invasion and metastasis. Three splice variants that encode different isoforms have been identified for this gene. (provided by RefSeq)
Aliases: EMS1, FLJ34459, CTTN
- Molekulargewicht
- 80kDa
- Gen-ID
- 2017
- HGNC
- 2017
- UniProt
- Q14247
- Pathways
- MAPK Signalweg
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