Cytokeratin 5 Antikörper

Produktnummer ABIN969078

Produktdetails anti-Cytokeratin 5 Antikörper

Target: Cytokeratin 5 (KRT5) (Keratin 5 (KRT5))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Cytokeratin 5 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), ELISA

Verwendungszweck: Cytokeratin 5 Antibody

Aufreinigung: Ascitic fluid

Immunogen: Purified recombinant fragment of CK5 expressed in E. Coli.

Klon: 3E2F1

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: ELISA: 1/10000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Referenzen für anti-Cytokeratin 5 Antikörper (ABIN969078)

Canedo-Patzi, León-Bojorge, de Ortíz-Hidalgo: "[Adenomatoid tumor of the genital tract. Clinical, pathological and immunohistochemical study in 9 cases]." in: Gaceta médica de México, Vol. 142, Issue 1, pp. 59-66, (2006) (PubMed).

Leibl, Moinfar: "Mammary NOS-type sarcoma with CD10 expression: a rare entity with features of myoepithelial differentiation." in: The American journal of surgical pathology, Vol. 30, Issue 4, pp. 450-6, (2006) (PubMed).

Details zu Cytokeratin 5

Target: Cytokeratin 5 (KRT5) (Keratin 5 (KRT5))

Andere Bezeichnung: Cytokeratin 5 (KRT5 Produkte)

Hintergrund:

Description: CK5 (keratin 5) is a member of the keratin gene family. Biochemically, most members of the CK family fall into one of two classes, type I (acidic polypeptides) and type II (basic polypeptides). The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the basal layer of the epidermis with family member KRT14. The type II cytokeratins are clustered in a region of chromosome 12q12-q13. At least one member of the acidic family and one member of the basic family is expressed in all epithelial cells. Cytokeratin 5 is expressed in normal basal cells. Mutations of the Cytokeratin5 gene (KRT5) have been shown to result in the autosomal dominant disorderepidermolysis bullosa (EB). Defects in KRT5 are a cause of epidermolysis bullosa simplex.

Aliases: K5, DDD, EBS2, KRT5A, KRT5

Gen-ID: 3852

HGNC: 3852

UniProt: P13647