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KRT8 Antikörper (AA 391-483)

Name: KRT8 Antikörper (AA 391-483)
Brand: antibodies-online
SKU: ABIN969080
Price: 631.53 EUR
Availability: InStock

KRT8 Reaktivität: Human WB, IHC, ELISA, ICC Wirt: Maus Monoclonal 8A5D12 unconjugated

Immunohistochemical analysis of paraffin-embedded human Kidney tissues using CK8 mouse mAb (KRT8 Antikörper (AA 391-483))

IHC

Confocal immunofluorescence analysis of methanol-fixed ECA109 cells (left) and HepG2 cells (right) using CK8 mouse mAb (green), showing cytoplasmic localization. (KRT8 Antikörper (AA 391-483))

Western blot analysis using CK8 mouse mAb against A549 (1), Hela (2), MCF-7 (3), A431 (4) and HepG2 (5) cell lysate. (KRT8 Antikörper (AA 391-483))

Immunohistochemical analysis of paraffin-embedded human breast carcinoma (A), lung cancer (B) and ovarian cancer tissue (C), showing membrane and cytoplasmic localization with DAB staining using CK8 mouse mAb. (KRT8 Antikörper (AA 391-483))

IHC

4 Abbildungen

(1 reference)

Produktnummer ABIN969080

Datenblatt (PDF)

Target Alle KRT8 Antikörper anzeigen

KRT8 (Keratin 8 (KRT8))
Bindungsspezifität
23

16

13

13

11

8

6

6

5

5

4

4

4

3

3

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 391-483
Reaktivität
265

86

82

33

33

31

30

16

14

10

8

5

4

3

2

1

1

1
Human
Wirt
148

125

3
Maus
Passende Sekundärantikörper
Klonalität
146

128
Monoklonal
Konjugat
144

22

16

9

4

4

4

4

4

4

3

3

3

3

3

3

3

3

3

3

3

3

3

3

3

3

3

3

2

2

2

1
Dieser KRT8 Antikörper ist unkonjugiert
Applikation
170

100

98

81

66

49

41

40

29

29

24

17

5

5

4

4

2

2

1

1
Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunocytochemistry (ICC)

Verwendungszweck

Cytokeratin 8 Antibody

Aufreinigung

Ascitic fluid

Immunogen

Purified recombinant fragment of human Cytokeratin (aa391-483) expressed in E. Coli.

Klon

8A5D12

Isotyp

IgG1

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Applikationshinweise

ELISA: 1/10000
ICC: 1/200 - 1/1000

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Buffer

Ascitic fluid containing 0.03 % sodium azide.

Konservierungsmittel

Sodium azide

Vorsichtsmaßnahmen

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung

4 °C,-20 °C

Informationen zur Lagerung

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Walker, Harris, Holloway, McKenzie, Wells, Robinson, Morris: "Cytokeratin KRT8/18 expression differentiates distinct subtypes of grade 3 invasive ductal carcinoma of the breast." in: Cancer genetics and cytogenetics, Vol. 178, Issue 2, pp. 94-103, (2007) (PubMed).
Target

KRT8 (Keratin 8 (KRT8))

Andere Bezeichnung

Cytokeratin 8 (KRT8 Produkte)

Synonyme

CARD2 antikoerper, CK-8 antikoerper, CK8 antikoerper, CYK8 antikoerper, K2C8 antikoerper, K8 antikoerper, KO antikoerper, AA960620 antikoerper, AL022697 antikoerper, AU019895 antikoerper, Card2 antikoerper, EndoA antikoerper, Krt-2.8 antikoerper, Krt2-8 antikoerper, CYKER antikoerper, KRT2-8 antikoerper, KERATIN8 antikoerper, ck8 antikoerper, cyk8 antikoerper, k2c8 antikoerper, card2 antikoerper, krt2-5 antikoerper, MGC69490 antikoerper, KRT8 antikoerper, DreK8 antikoerper, cb186 antikoerper, krt2-8 antikoerper, sb:cb186 antikoerper, wu:fa20h05 antikoerper, wu:fa95h10 antikoerper, wu:fb96c06 antikoerper, zf-K8 antikoerper, zfk8 antikoerper, DKFZp468F2127 antikoerper, keratin 8 antikoerper, keratin 8 S homeolog antikoerper, KRT8 antikoerper, Krt8 antikoerper, krt8.S antikoerper, krt8 antikoerper

Hintergrund

Description: Cytokeratin 8, also known as CK8, KRT8, K8. Entrez Protein NP_002264. It is a member of the type II keratin family.Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells.It typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in this gene cause cryptogenic cirrhosis.
Aliases: CK8, CYK8, K2C8, KRT8

Molekulargewicht

54kDa

Gen-ID

3856

HGNC

3856

UniProt

P05787