EPH Receptor A3 Antikörper (AA 751-983)

Produktnummer ABIN969101

Produktdetails anti-EPH Receptor A3 Antikörper

Target: EPH Receptor A3 (EPHA3)

Bindungsspezifität: AA 751-983

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser EPH Receptor A3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Aufreinigung: purified

Immunogen: Purified recombinant fragment of EphA3 (aa751-983) expressed in E. coli.

Klon: 6C1B6

Isotyp: IgG2b

Anwendungsinformationen

Applikationshinweise: ELISA: 1:10000, WB: 1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: 4°C, -20°C for long term storage

Referenzen für anti-EPH Receptor A3 Antikörper (ABIN969101)

Janes, Saha, Barton, Kolev, Wimmer-Kleikamp, Nievergall, Blobel, Himanen, Lackmann, Nikolov: "Adam meets Eph: an ADAM substrate recognition module acts as a molecular switch for ephrin cleavage in trans." in: Cell, Vol. 123, Issue 2, pp. 291-304, (2005) (PubMed).

Details zu EPH Receptor A3

Target: EPH Receptor A3 (EPHA3)

Andere Bezeichnung: EphA3 (EPHA3 Produkte)

Synonyme: EK4 antikoerper, ETK antikoerper, ETK1 antikoerper, HEK antikoerper, HEK4 antikoerper, TYRO4 antikoerper, EPHA3 antikoerper, AW492086 antikoerper, Cek4 antikoerper, End3 antikoerper, Hek antikoerper, Hek4 antikoerper, Mek4 antikoerper, Tyro4 antikoerper, CEK4 antikoerper, EPH receptor A3 antikoerper, ephrin type-A receptor 3 antikoerper, Eph receptor A3 antikoerper, EPHA3 antikoerper, LOC100439679 antikoerper, Epha3 antikoerper

Hintergrund:

Description: EphA3: EPH receptor A3. This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. This gene encodes a protein that binds ephrin-A ligands. Two alternatively spliced transcript variants have been described for this gene.

Aliases: SEK, HEK8, TYRO1

Gen-ID: 2043

HGNC: 2043

Pathways: RTK Signalweg, Regulation of Cell Size