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ERN1 Antikörper (AA 282-433)

ERN1 Reaktivität: Human WB, ELISA, IHC Wirt: Maus Monoclonal 9F2 unconjugated
Produktnummer ABIN969116
  • Target Alle ERN1 Antikörper anzeigen
    ERN1 (Endoplasmic Reticulum To Nucleus Signaling 1 (ERN1))
    Bindungsspezifität
    • 16
    • 16
    • 6
    • 6
    • 5
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 282-433
    Reaktivität
    • 69
    • 51
    • 45
    • 16
    • 1
    Human
    Wirt
    • 68
    • 4
    • 3
    • 1
    Maus
    Klonalität
    • 70
    • 6
    Monoklonal
    Konjugat
    • 32
    • 8
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Dieser ERN1 Antikörper ist unkonjugiert
    Applikation
    • 71
    • 35
    • 30
    • 26
    • 26
    • 10
    • 9
    • 8
    • 8
    • 6
    • 5
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    Verwendungszweck
    ERN1 Antibody
    Aufreinigung
    Ascitic fluid
    Immunogen
    Purified recombinant fragment of human ERN1(aa282-433) expressed in E. Coli.
    Klon
    9F2
    Isotyp
    IgG1
    Top Product
    Discover our top product ERN1 Primärantikörper
  • Applikationshinweise
    ELISA: 1/10000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Ascitic fluid containing 0.03 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Lin, Li, Yasumura, Cohen, Zhang, Panning, Shokat, Lavail, Walter: "IRE1 signaling affects cell fate during the unfolded protein response." in: Science (New York, N.Y.), Vol. 318, Issue 5852, pp. 944-9, (2007) (PubMed).

    Huang, Tan, Yoshida, Mori, Ma, Yen: "Activation of hepatitis B virus S promoter by a cell type-restricted IRE1-dependent pathway induced by endoplasmic reticulum stress." in: Molecular and cellular biology, Vol. 25, Issue 17, pp. 7522-33, (2005) (PubMed).

    Shang, Lehrman: "Discordance of UPR signaling by ATF6 and Ire1p-XBP1 with levels of target transcripts." in: Biochemical and biophysical research communications, Vol. 317, Issue 2, pp. 390-6, (2004) (PubMed).

  • Target
    ERN1 (Endoplasmic Reticulum To Nucleus Signaling 1 (ERN1))
    Andere Bezeichnung
    ERN1 (ERN1 Produkte)
    Hintergrund

    Description: The protein encoded by this gene is the ER to nucleus signalling 1 protein, a human homologue of the yeast Ire1 gene product. This protein possesses intrinsic kinase activity and an endoribonuclease activity and it is important in altering gene expression as a response to endoplasmic reticulum-based stress signals.

    Aliases: IRE1, IRE1P, IRE1a, hIRE1p, FLJ30999, MGC163277, MGC163279, ERN1

    Molekulargewicht
    109kDa
    Gen-ID
    2081
    HGNC
    2081
    UniProt
    O75460
    Pathways
    ER-Nucleus Signaling, Unfolded Protein Response
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