FABP2 Antikörper

Produktnummer ABIN969124

Produktdetails anti-FABP2 Antikörper

Target: FABP2 (Fatty Acid Binding Protein 2, Intestinal (FABP2))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser FABP2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunocytochemistry (ICC), Flow Cytometry (FACS)

Verwendungszweck: FABP2 Antibody

Aufreinigung: Ascitic fluid

Immunogen: Purified recombinant fragment of human FABP2 expressed in E. Coli.

Klon: 9A9B7B3

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise:

ELISA: 1/10000

FCM: 1/200 - 1/400

ICC: 1/200 - 1/1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Referenzen für anti-FABP2 Antikörper (ABIN969124)

Fisher, Li, Burwinkel, Kühr, Hoffmann, Möhlig, Spranger, Pfeiffer, Boeing, Schrezenmeir, Döring: "Preliminary evidence of FABP2 A54T polymorphism associated with reduced risk of type 2 diabetes and obesity in women from a German cohort." in: Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et métabolisme, Vol. 38, Issue 5, pp. 341-5, (2006) (PubMed).

Kim, Yun, Byun, Yoo, Lee, Suh: "Codon 54 polymorphism of the fatty acid binding protein 2 gene is associated with increased fat oxidation and hyperinsulinemia, but not with intestinal fatty acid absorption in Korean men." in: Metabolism: clinical and experimental, Vol. 50, Issue 4, pp. 473-6, (2001) (PubMed).

Georgopoulos, Aras, Tsai: "Codon-54 polymorphism of the fatty acid-binding protein 2 gene is associated with elevation of fasting and postprandial triglyceride in type 2 diabetes." in: The Journal of clinical endocrinology and metabolism, Vol. 85, Issue 9, pp. 3155-60, (2000) (PubMed).

Details zu FABP2

Target: FABP2 (Fatty Acid Binding Protein 2, Intestinal (FABP2))

Andere Bezeichnung: FABP2 (FABP2 Produkte)

Synonyme: I-FABP antikoerper, ifabp antikoerper, zgc:92264 antikoerper, IFABP antikoerper, fabpi antikoerper, i-fabp antikoerper, fabp2-A antikoerper, FABP2 antikoerper, FABPI antikoerper, FABP antikoerper, Fabpi antikoerper, fabp2 antikoerper, fabp2a antikoerper, fatty acid binding protein 2, intestinal antikoerper, fatty acid binding protein 2 antikoerper, fatty acid binding protein 2 L homeolog antikoerper, fabp2 antikoerper, FABP2 antikoerper, Fabp2 antikoerper, fabp2.L antikoerper

Hintergrund:

Description:

The intracellular fatty acid-binding proteins (FABPs) belong to a multigene family with nearly twenty identified members. FABPs are divided into at least three distinct types, namely the hepatic-, intestinal- and cardiac-type. They form 14-15 kDa proteins and are thought to participate in the uptake, intracellular metabolism and/or transport of long-chain fatty acids. They may also be responsible in the modulation of cell growth and proliferation. Intestinal fatty acid-binding protein 2 gene contains four exons and is an abundant cytosolic protein in small intestine epithelial cells. This gene has a polymorphism at codon 54 that identified an alanine-encoding allele and a threonine-encoding allele. Thr-54 protein is associated with increased fat oxidation and insulin resistance. Genetic variation in FABP2 may thus contribute to interindividual variation in the response of plasma lipoproteins to different dietary fibres, but the mechanism does not appear to be related to increases in fecal bile acid secretion.

Aliases: FABPI, I-FABP, MGC133132, FABP2

Molekulargewicht: 15kDa

Gen-ID: 2169

HGNC: 2169

UniProt: P12104