FGFR1 Antikörper (AA 22-376)

Produktnummer ABIN969138

Produktdetails anti-FGFR1 Antikörper

Target: FGFR1 (Fibroblast Growth Factor Receptor 1 (FGFR1))

Bindungsspezifität: AA 22-376

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser FGFR1 Antikörper ist unkonjugiert

Applikation: ELISA

Verwendungszweck: FGFR1 Antibody

Aufreinigung: Ascitic fluid

Immunogen: Purified recombinant extracellular fragment of human FGFR1 (aa22-376) fused with hIgGFc tag expressed in HEK293 cells.

Klon: 3D4F7

Isotyp: IgG2b

Anwendungsinformationen

Applikationshinweise: ELISA: 1/10000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Referenzen für anti-FGFR1 Antikörper (ABIN969138)

Elbauomy Elsheikh, Green, Lambros, Turner, Grainge, Powe, Ellis, Reis-Filho: "FGFR1 amplification in breast carcinomas: a chromogenic in situ hybridisation analysis." in: Breast cancer research : BCR, Vol. 9, Issue 2, pp. R23, (2007) (PubMed).

Magnusson, Ronca, DellEra, Carlstedt, Jakobsson, Partanen, Dimberg, Claesson-Welsh: "Fibroblast growth factor receptor-1 expression is required for hematopoietic but not endothelial cell development." in: Arteriosclerosis, thrombosis, and vascular biology, Vol. 25, Issue 5, pp. 944-9, (2005) (PubMed).

Hu, Fang, Dunham, Prada, Stachowiak, Stachowiak: "90-kDa ribosomal S6 kinase is a direct target for the nuclear fibroblast growth factor receptor 1 (FGFR1): role in FGFR1 signaling." in: The Journal of biological chemistry, Vol. 279, Issue 28, pp. 29325-35, (2004) (PubMed).

Details zu FGFR1

Target: FGFR1 (Fibroblast Growth Factor Receptor 1 (FGFR1))

Andere Bezeichnung: FGFR1 (FGFR1 Produkte)

Synonyme: FGFR antikoerper, fgfr antikoerper, X1FGFR antikoerper, XFGFR-1 antikoerper, XFGFRA2 antikoerper, bfgfr antikoerper, cek antikoerper, fgfr1 antikoerper, flg antikoerper, flt-2 antikoerper, flt2 antikoerper, kal2 antikoerper, ogd antikoerper, xfgfr1 antikoerper, CG7223 antikoerper, CT22273 antikoerper, CT39172 antikoerper, DFGF-R1 antikoerper, DFGF-R2 antikoerper, DFR-1 antikoerper, DFR1 antikoerper, DFR1/DFGF-R2 antikoerper, DPR3 antikoerper, DTRK(FR1) antikoerper, Dfr-1 antikoerper, Dfr1 antikoerper, DmHD-38 antikoerper, Dmel\\CG7223 antikoerper, Dtk1 antikoerper, EMS2 antikoerper, FGF-R2 antikoerper, FGFR2 antikoerper, FR1 antikoerper, Fr1 antikoerper, HD-38 antikoerper, HTL/FGFR1 antikoerper, Htl antikoerper, Tk1 antikoerper, dtk1 antikoerper, i100 antikoerper, i150 antikoerper, i79 antikoerper, j372 antikoerper, cd331 antikoerper, fgfbr antikoerper, fgfr-1 antikoerper, hbgfr antikoerper, n-sam antikoerper, ach antikoerper, cd333 antikoerper, cek2 antikoerper, fgfr-3 antikoerper, hsfgfr3ex antikoerper, jtk4 antikoerper, BFGFR antikoerper, CD331 antikoerper, CEK antikoerper, FGFBR antikoerper, FGFR-1 antikoerper, FLG antikoerper, FLT-2 antikoerper, FLT2 antikoerper, HBGFR antikoerper, HH2 antikoerper, KAL2 antikoerper, N-SAM antikoerper, OGD antikoerper, bFGF-R-1 antikoerper, AW208770 antikoerper, Eask antikoerper, Fgfr-1 antikoerper, Flt-2 antikoerper, Hspy antikoerper, FLG-1 antikoerper, FGFRI antikoerper, x1fgfr antikoerper, cb231 antikoerper, sb:cb231 antikoerper, fibroblast growth factor receptor antikoerper, fibroblast growth factor receptor 1 S homeolog antikoerper, basic fibroblast growth factor receptor 1 antikoerper, heartless antikoerper, fibroblast growth factor receptor 1 antikoerper, fibroblast growth factor receptor 3 (achondroplasia, thanatophoric dwarfism) L homeolog antikoerper, Fibroblast growth factor receptor 1 antikoerper, fibroblast growth factor receptor 1 L homeolog antikoerper, fibroblast growth factor receptor 1a antikoerper, FGFR antikoerper, fgfr antikoerper, fgfr1.S antikoerper, CpipJ_CPIJ005849 antikoerper, htl antikoerper, fgfr1 antikoerper, fgfr3.L antikoerper, FGFR1 antikoerper, Fgfr1 antikoerper, fgfr1.L antikoerper, fgfr1a antikoerper

Hintergrund:

Description: Fibroblast growth factor receptor 1 (FGFR1), also known as basic fibroblast growth factor receptor 1, fms-related tyrosine kinase-2 / Pfeiffer syndrome, and CD331, is a receptor tyrosine kinase whose ligands are specific members of the fibroblast growth factor family. FGFR1 has been shown to be associated with Pfeiffer syndrome. It is a member of the fibroblast growth factor receptor (FGFR) family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein consists of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. This particular family member binds both acidic and basic fibroblast growth factors and is involved in limb induction.

Aliases: CEK, FLG, OGD, FLT2, KAL2, BFGFR, CD331, FGFBR, HBGFR

Molekulargewicht: 92kDa

Gen-ID: 2260

HGNC: 2260

UniProt: P11362

Pathways: RTK Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Sensory Perception of Sound, Stem Cell Maintenance, S100 Proteine