FGG Antikörper
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- Target Alle FGG Antikörper anzeigen
- FGG (Fibrinogen gamma Chain (FGG))
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser FGG Antikörper ist unkonjugiert
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Applikation
- ELISA, Immunocytochemistry (ICC)
- Verwendungszweck
- FGG Antibody
- Aufreinigung
- Ascitic fluid
- Immunogen
- Purified recombinant fragment of human FGG expressed in E. Coli.
- Klon
- 5A6
- Isotyp
- IgG2b
- Top Product
- Discover our top product FGG Primärantikörper
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- Applikationshinweise
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ELISA: 1/10000
ICC: 1/200 - 1/1000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- Ascitic fluid containing 0.03 % sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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The pleiotropic role of the fibrinogen gamma' chain in hemostasis." in: Blood, Vol. 114, Issue 19, pp. 3994-4001, (2009) (PubMed).
: "Impaired protofibril formation in fibrinogen gamma N308K is due to altered D:D and "A:a" interactions." in: Biochemistry, Vol. 48, Issue 36, pp. 8656-63, (2009) (PubMed).
: "
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The pleiotropic role of the fibrinogen gamma' chain in hemostasis." in: Blood, Vol. 114, Issue 19, pp. 3994-4001, (2009) (PubMed).
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- Target
- FGG (Fibrinogen gamma Chain (FGG))
- Andere Bezeichnung
- FGG (FGG Produkte)
- Hintergrund
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Description: The protein encoded by this gene is the gamma component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in this gene lead to several disorders, including dysfibrinogenemia, hypofibrinogenemia and thrombophilia. Alternative splicing results in two transcript variants encoding different isoforms.
Aliases: FGG
- Molekulargewicht
- 52kDa
- Gen-ID
- 2266
- HGNC
- 2266
- UniProt
- P02679
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