Glucose-6-Phosphate Dehydrogenase Antikörper

Produktnummer ABIN969161

Produktdetails anti-Glucose-6-Phosphate Dehydrogenase Antikörper

Target: Glucose-6-Phosphate Dehydrogenase (G6PD)

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Glucose-6-Phosphate Dehydrogenase Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS)

Verwendungszweck: G6PD Antibody

Aufreinigung: Ascitic fluid

Immunogen: Purified recombinant fragment of human G6PD expressed in E. Coli.

Klon: 5E12

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise:

ELISA: 1/10000

FCM: 1/200 - 1/400

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Referenzen für anti-Glucose-6-Phosphate Dehydrogenase Antikörper (ABIN969161)

Louicharoen, Patin, Paul, Nuchprayoon, Witoonpanich, Peerapittayamongkol, Casademont, Sura, Laird, Singhasivanon, Quintana-Murci, Sakuntabhai: "Positively selected G6PD-Mahidol mutation reduces Plasmodium vivax density in Southeast Asians." in: Science (New York, N.Y.), Vol. 326, Issue 5959, pp. 1546-9, (2009) (PubMed).

Brajovich, Rucci, Acosta, Cotorruelo, García Borrás, Racca, Biondi, Racca: "Effects of aging on antioxidant response and phagocytosis in senescent erythrocytes." in: Immunological investigations, Vol. 38, Issue 6, pp. 551-9, (2009) (PubMed).

Details zu Glucose-6-Phosphate Dehydrogenase

Target: Glucose-6-Phosphate Dehydrogenase (G6PD)

Andere Bezeichnung: G6PD (G6PD Produkte)

Hintergrund:

Description: This gene encodes glucose-6-phosphate dehydrogenase. This protein is a cytosolic enzyme encoded by a housekeeping X-linked gene whose main function is to produce NADPH, a key electron donor in the defense against oxidizing agents and in reductive biosynthetic reactions. G6PD is remarkable for its genetic diversity. Many variants of G6PD, mostly produced from missense mutations, have been described with wide ranging levels of enzyme activity and associated clinical symptoms. G6PD deficiency may cause neonatal jaundice, acute hemolysis, or severe chronic non-spherocytic hemolytic anemia. Two transcript variants encoding different isoforms have been found for this gene.

Aliases: G6PD1

Molekulargewicht: 59kDa

Gen-ID: 2539

HGNC: 2539

UniProt: P11413

Pathways: Regulation of Systemic Arterial Blood Pressure by Hormones