HDAC4 Antikörper

Produktnummer ABIN969190

Produktdetails anti-HDAC4 Antikörper

Target: HDAC4 (Histone Deacetylase 4 (HDAC4))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser HDAC4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Verwendungszweck: HDAC4 Antibody

Aufreinigung: Purified antibody

Immunogen: Purified recombinant fragment of human HDAC4 expressed in E. Coli.

Klon: 7B2

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: ELISA: 1/10000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified antibody in PBS containing 0.05 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Referenzen für anti-HDAC4 Antikörper (ABIN969190)

Shao, Li, Zhang, Liu, Liu, Zhao, Shen, Li: "Involvement of histone deacetylation in MORC2-mediated down-regulation of carbonic anhydrase IX." in: Nucleic acids research, Vol. 38, Issue 9, pp. 2813-24, (2010) (PubMed).

Ficner: "Novel structural insights into class I and II histone deacetylases." in: Current topics in medicinal chemistry, Vol. 9, Issue 3, pp. 235-40, (2009) (PubMed).

Nishino, Miyazaki, Hoshino, Miwa, Horinouchi, Yoshida: "14-3-3 regulates the nuclear import of class IIa histone deacetylases." in: Biochemical and biophysical research communications, Vol. 377, Issue 3, pp. 852-6, (2008) (PubMed).

Details zu HDAC4

Target: HDAC4 (Histone Deacetylase 4 (HDAC4))

Andere Bezeichnung: HDAC4 (HDAC4 Produkte)

Synonyme: CG1770 antikoerper, DHDAC4 antikoerper, Dmel\\CG1770 antikoerper, GC1770 antikoerper, HDAC antikoerper, HDAC4a antikoerper, dHDAC4 antikoerper, dmHDA405 antikoerper, hdac4 antikoerper, dana_GLEANR_19966 antikoerper, DanaGF18710 antikoerper, GF18710 antikoerper, HDAC4 antikoerper, AHO3 antikoerper, BDMR antikoerper, HA6116 antikoerper, HD4 antikoerper, HDAC-4 antikoerper, HDAC-A antikoerper, HDACA antikoerper, 4932408F19Rik antikoerper, AI047285 antikoerper, wu:fa96d08 antikoerper, wu:fc56f08 antikoerper, zgc:152701 antikoerper, histone deacetylase 4 antikoerper, hypothetical protein antikoerper, Histone deacetylase 4 antikoerper, GF18710 gene product from transcript GF18710-RC antikoerper, PTRG_03699 antikoerper, PGTG_15512 antikoerper, HDAC4 antikoerper, Dana\GF18710 antikoerper, Hdac4 antikoerper, hdac4 antikoerper

Hintergrund:

Description: Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. This protein does not bind DNA directly, but through transcription factors MEF2C and MEF2D. It seems to interact in a multiprotein complex with RbAp48 and HDAC3.

Aliases: HD4, HDACA, HA6116, HDAC-A, KIAA0288, HDAC4

Molekulargewicht: 119kDa

Gen-ID: 9759

HGNC: 9759

UniProt: P56524

Pathways: Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Regulation of Carbohydrate Metabolic Process