HFE Antikörper
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- Target Alle HFE Antikörper anzeigen
- HFE (Hemochromatosis (HFE))
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser HFE Antikörper ist unkonjugiert
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Applikation
- ELISA, Immunocytochemistry (ICC)
- Verwendungszweck
- HFE Antibody
- Aufreinigung
- Ascitic fluid
- Immunogen
- Purified recombinant fragment of human HFE expressed in E. Coli.
- Klon
- 3F1
- Isotyp
- IgG1
- Top Product
- Discover our top product HFE Primärantikörper
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- Applikationshinweise
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ELISA: 1/10000
ICC: 1/200 - 1/1000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- Ascitic fluid containing 0.03 % sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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PTEN identified as important risk factor of chronic obstructive pulmonary disease." in: Respiratory medicine, Vol. 103, Issue 12, pp. 1866-70, (2009) (PubMed).
: "HFE mutations modulate the effect of iron on serum hepcidin-25 in chronic hemodialysis patients." in: Clinical journal of the American Society of Nephrology : CJASN, Vol. 4, Issue 8, pp. 1331-7, (2009) (PubMed).
: "
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PTEN identified as important risk factor of chronic obstructive pulmonary disease." in: Respiratory medicine, Vol. 103, Issue 12, pp. 1866-70, (2009) (PubMed).
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- Target
- HFE (Hemochromatosis (HFE))
- Andere Bezeichnung
- HFE (HFE Produkte)
- Synonyme
- HFE1 antikoerper, HH antikoerper, HLA-H antikoerper, MVCD7 antikoerper, TFQTL2 antikoerper, MR2 antikoerper, hemochromatosis antikoerper, HFE antikoerper, Hfe antikoerper
- Hintergrund
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Description: The protein encoded by this gene is a membrane protein that is similar to MHC class I-type proteins and associates with beta2-microglobulin (beta2M). It is thought that this protein functions to regulate iron absorption by regulating the interaction of the transferrin receptor with transferrin. The iron storage disorder, hereditary haemochromatosis, is a recessive genetic disorder that results from defects in this gene. At least nine alternatively spliced variants have been described for this gene. Additional variants have been found but their full-length nature has not been determined.
Aliases: HH; HFE1; HLA-H; MVCD7; TFQTL2; MGC103790; dJ221C16.10.1
- Molekulargewicht
- 40kDa
- Gen-ID
- 3077
- HGNC
- 3077
- UniProt
- Q30201
- Pathways
- Transition Metal Ion Homeostasis, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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