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Hexokinase 1 Antikörper

HK1 Reaktivität: Human WB, ELISA, IHC, ICC, FACS Wirt: Maus Monoclonal 3A10 unconjugated
Produktnummer ABIN969195
  • Target Alle Hexokinase 1 (HK1) Antikörper anzeigen
    Hexokinase 1 (HK1)
    Reaktivität
    • 87
    • 46
    • 33
    • 7
    • 6
    • 6
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human
    Wirt
    • 96
    • 11
    Maus
    Klonalität
    • 87
    • 20
    Monoklonal
    Konjugat
    • 58
    • 17
    • 8
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    Dieser Hexokinase 1 Antikörper ist unkonjugiert
    Applikation
    • 86
    • 46
    • 37
    • 17
    • 16
    • 16
    • 11
    • 7
    • 7
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC), Flow Cytometry (FACS)
    Verwendungszweck
    HK1 Antibody
    Aufreinigung
    Ascitic fluid
    Immunogen
    Purified recombinant fragment of human HK1 expressed in E. Coli.
    Klon
    3A10
    Isotyp
    IgG1
    Top Product
    Discover our top product HK1 Primärantikörper
  • Applikationshinweise

    ELISA: 1/10000

    FCM: 1/200 - 1/400

    ICC: 1/200 - 1/1000

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Ascitic fluid containing 0.03 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Grupe, Li, Rowland, Nowotny, Hinrichs, Smemo, Kauwe, Maxwell, Cherny, Doil, Tacey, van Luchene, Myers, Wavrant-De Vrièze, Kaleem, Hollingworth, Jehu, Foy, Archer, Hamilton, Holmans, Morris, Catanese et al.: "A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease. ..." in: American journal of human genetics, Vol. 78, Issue 1, pp. 78-88, (2005) (PubMed).

    Stelzl, Worm, Lalowski, Haenig, Brembeck, Goehler, Stroedicke, Zenkner, Schoenherr, Koeppen, Timm, Mintzlaff, Abraham, Bock, Kietzmann, Goedde, Toksöz, Droege, Krobitsch, Korn, Birchmeier, Lehrach et al.: "A human protein-protein interaction network: a resource for annotating the proteome. ..." in: Cell, Vol. 122, Issue 6, pp. 957-68, (2005) (PubMed).

  • Target
    Hexokinase 1 (HK1)
    Andere Bezeichnung
    HK1 (HK1 Produkte)
    Hintergrund

    Description: The hexokinases utilize Mg-ATP as a phosphoryl donor to catalyze the first step of intracellular glucose metabolism, the conversion of glucose to glucose- 6-phosphate. Four hexokinase isoenzymes have been identified, including hexokinase I (HXK I), hexokinase II (HXK II), hexokinase III (HXK III) and hexokinase IV (HXK IV, also designated glucokinase or GCK). Hexokinases I-III each contain an N-terminal cluster of hydrophobic amino acids. Glucokinase lacks the N-terminal hydrophobic cluster. The hydrophobic cluster is thought to be necessary for membrane binding. This is substantiated by the finding that glucokinase has lower affinity for glucose than do the other hexokinases. HK I has been shown to be expressed in brain, kidney and heart tissues as well as in hepatoma cell lines.

    Aliases: HKI, HXK1, HK1-ta, HK1-tb, HK1-tc, HK1

    Molekulargewicht
    102kDa
    Gen-ID
    3098
    HGNC
    3098
    UniProt
    P19367
    Pathways
    Carbohydrate Homeostasis, Warburg Effekt
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