ICAM1 Antikörper (AA 28-480)
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- Target Alle ICAM1 Antikörper anzeigen
- ICAM1 (Intercellular Adhesion Molecule 1 (ICAM1))
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Bindungsspezifität
- AA 28-480
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser ICAM1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA
- Aufreinigung
- purified
- Immunogen
- Purified recombinant fragment of human ICAM1(28-480aa) expressed in E. coli.
- Klon
- 6G12
- Isotyp
- IgG1
- Top Product
- Discover our top product ICAM1 Primärantikörper
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- Applikationshinweise
- ELISA: 1:10000, WB: 1:500 - 1:2000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- Ascitic fluid containing 0.03 % sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
- 4°C, -20°C for long term storage
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Susceptibility to primary sclerosing cholangitis is associated with polymorphisms of intercellular adhesion molecule-1." in: Journal of hepatology, Vol. 40, Issue 3, pp. 375-9, (2004) (PubMed).
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Susceptibility to primary sclerosing cholangitis is associated with polymorphisms of intercellular adhesion molecule-1." in: Journal of hepatology, Vol. 40, Issue 3, pp. 375-9, (2004) (PubMed).
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- Target
- ICAM1 (Intercellular Adhesion Molecule 1 (ICAM1))
- Andere Bezeichnung
- ICAM1 (ICAM1 Produkte)
- Synonyme
- BB2 antikoerper, CD54 antikoerper, P3.58 antikoerper, Icam-1 antikoerper, Ly-47 antikoerper, MALA-2 antikoerper, ICAM antikoerper, ICAM-1 antikoerper, ICAM1 antikoerper, intercellular adhesion molecule 1 antikoerper, intercellular adhesion molecule-1 antikoerper, ICAM1 antikoerper, Icam1 antikoerper, ICAM-1 antikoerper
- Substanzklasse
- Viral Protein
- Hintergrund
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Description: ICAM1 is a 85-110 kDa single chain type 1 integral membrane glycoprotein with an extracellular domain of five immunoglobulin superfamily repeats, a transmembrane region and a cytoplasmic domain. It shares considerable amino acid sequence homology with ICAM3 and with ICAM2. ICAM1 is expressed by activated endothelial cells. It is detected on cells of many other lineages (e.g. epithelial cells, fibroblasts, chondrocytes, B lymphocytes, T lymphocytes (low), monocytes, macrophages, dendritic cells and neutrophils), with lower levels that increase in inflammation. ICAM1 is also detected in some carcinoma and melanoma cells. Soluble ICAM1 is detectable in the plasma and is elevated in patients with various inflammatory syndromes. It is the receptor for rhinoviruses and malaria.
Aliases: BB2, CD54, P3.58, ICAM1
- Molekulargewicht
- 57.8 kDa
- Gen-ID
- 3383
- HGNC
- 3383
- Pathways
- Cellular Response to Molecule of Bacterial Origin, Regulation of Actin Filament Polymerization, Carbohydrate Homeostasis, Regulation of Leukocyte Mediated Immunity, Thromboxane A2 Receptor Signaling
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